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INDEX

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The following sites provide on-line information about Combinatorial Chemistry:


5z.com: A member of the Combi-Web Consortium, is a web site that covers a broad scope of topics related to molecular diversity and combinatorial chemistry and provides online information on patents, articles, reviews, and books. The 5z.com website is maintained by Dr. Michal Lebl.


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Abbott Laboratories: Abbott Laboratories has at its site information on combinatorial chemistry entitled "Introduction to Combinatorial Chemistry with Bill Kurtis". To visit this site click here.

About.com: About.com has an online site dedicated to combinatorial chemistry. To visit this site click here

Advanced ChemTech (ACT): ACT, a company that offers semiautomated synthesizer, resins, chemicals and consumables, has at its web site a support section with information related to combinatorial chemistry such as references, abstracts, resin protocols and application notes. To view this information click here.

Affymax Research Institute: Affymax, now part of Glaxo-Wellcome, focuses in the field of combinatorial chemistry. Its web site includes a section on patents and publications. To read this section click here

Albany Molecular Research Inc. (AMRI): Albany Molecular Research Inc., a company that offers chemical and research services, has at its website a ChemLink page with links to scientific web sites and a Technical Report page with experimental synthesis procedures. To visit AMRI's ChemLink page click here. To visit AMRI's Technical Report page click here

Aldrich: See Sigma-Aldrich.

American Chemical Society (ACS): ACS has online a compilation of hot articles on combinatorial chemistry. Here you have a summary:

 
Today's Chemist at Work Nov 2003 Combicat Can: Catalyst makers are looking to larger throughputs (PDF file).

Today's Chemist at Work

July 2003 Combichem: Fueling pharma (PDF file).
Modern Drug Discovery Sept 2003 Combichem QC (PDF file).
Modern Drug Discovery Sept 2003 Combinatorial neural networks (PDF file).
Modern Drug Discovery June 2003 Chirality in a combinatorial age (PDF file).
Modern Drug Discovery May 2003 Combi-extensions (covering Sunesis Pharmaceuticals Inc.'s extended tethering strategy) (PDF file).
Modern Drug Discovery Feb 2003 Scanning the code for combichem
Modern Drug Discovery Feb 2003 Patents and Property
Modern Drug Discovery August 2002 Grabbing the golden bead
Modern Drug Discovery June 2002 Combichem scavenging
Modern Drug Discovery Feb 2002 Rationalizing combi-chem
Modern Drug Discovery August 2001 The Nuke's the Thing for Synthesis
Modern Drug Discovery August 2001 Educating for combichem

Modern Drug Discovery

Feb 2001

Comprehensive Survey Of Combinatorial Library Synthesis: 1999

Modern Drug Discovery

Feb 2001

Enlisting Combichem To Fight Cancer

Modern Drug Discovery

Jul/Aug 2000

Sorting Out Combinatorial Chaos

Modern Drug Discovery

Jul/Aug 1999

Combinatorial Biosynthesis- Panning For Pharmaceutical Gold

J.Comb.Chem. Oct 2003 Comprehensive Survey of Combinatorial Library Synthesis: 2002
J.Comb.Chem. May 2003 Chiral Recognition: Design and Preparation of Chiral Stationary Phases Using Selectors Derived from Ugi Multicomponent Condensation Reactions and a Combinatorial Approach
J.Comb.Chem. Jan 2003 Combinatorial Electrochemical Synthesis and Characterization of Tungsten-Based Mixed-Metal Oxides
J.Comb.Chem. Dec 2002 Preparation of Thioamide Building Blocks via Microwave-Promoted Three-Component Kindler Reactions
J.Comb.Chem. Dec 2002 Glycopeptides as Oligosaccharide Mimics: High Affinity Sialopeptide Ligands for Sialoadhesin from Combinatorial Libraries
J.Comb.Chem. Aug 2002 Comprehensive Survey of Combinatorial Library Synthesis: 2001
J.Comb.Chem. Feb 2002 Dendritic Aliphatic Polyethers as High-Loading Soluble Supports for Carbonyl Compounds and Parallel Membrane Separation Techniques
J.Comb.Chem. Jan 2002 Development of a System To Evaluate Compound Identity, Purity, and Concentration in a Single Experiment and Its Application in Quality Assessment of Combinatorial Libraries and Screening Hits
J.Comb.Chem. Oct 2001 Comprehensive Survey of Combinatorial Library Synthesis: 2000
J.Comb.Chem. Sept-Oct 2000 Comprehensive Survey of Combinatorial Library Synthesis: 1999

J.Comb.Chem.

Aug 2000

Recent Advances In The Preparation Of Heterocycles On Solid Support: A Review Of The Literature

J.Comb.Chem.

Jun 2000

Spatially Addressed Synthesis of Amino- and Amino-Oxy-Substituted 1,3,5-Triazine Arrays on Polymeric Membranes

J.Comb.Chem.

Oct 1999

Selection of Modified Oligonucleotides with Increased Target Affinity via MALDI-Monitored Nuclease Survival Assays

J.Comb.Chem.

Jul 1999

Comprehensive Survey Of Combinatorial Library Synthesis- 1998

J.Comb.Chem.

Jun 1999

Comparison Of Resin And Solution Screening Methodologies In Combinatorial Chemistry And The Identification Of A 100 nM Inhibitor Of Trypanothione Reductase

J.Comb.Chem.

Dec 1998

Parallel personal comments on "classical" papers in combinatorial chemistry

ChemTech

May 1997

Taming The Combinatorial Centipede

C&E News Oct 2003 The Many Faces of Combinatorial Chemistry.
C&E News July 2003 QUICK DISCOVERY: Combinatorial screening methods are catching on for improving catalysts used in the manufacture of bulk chemicals.
C&E News April 2003 PEPTIDES ON DEMAND: Bruce Merrifield's 1963 paper paved the way for automated synthesis of peptides and proteins.
C&E News April 2003 COMBINATORIAL MATERIALS: FINDING CATALYSTS FASTER.
C&E News March 2003 Small-molecule peptide hybrids created.
C&E News March 2003 New dimension to combinatorial synthesis.
C&E News March 2003 THE SMALL-MOLECULE APPROACH TO BIOLOGY: Chemical genetics and diversity-oriented organic synthesis make possible the systematic exploration of biology.
C&E News Feb 2003 Nonpeptides improve on peptide.
C&E News Nov 2002 Combinatorial Chemistry
C&E News Nov 2002 Remarkable Complexity From One Pot.
C&E News August 2001 Combinatorial Chemistry
C&E News August 2001 Inorganics Go Combinatorial
C&E News June 2001 New Alternative to Bead Synthesis
C&E News January 2001 Combinatorial Rearrangments

C&E News

July 2000

Combinatorial Encoding Technique: A Lucky Charm

C&E News

July 2000

Combinatorial Synthesis Hits The Spot

C&E News

May 2000

A Great Cultural Change

C&E News

May 2000

Materials A La Combi

C&E News

May 2000

Combinatorial Chemistry: Redefining The Scientific Method for Drug Discovery Of Drugs And Materials

C&E News

Mar 2000

ChemNavigator.com Addresses Combinatorial Chemistry Market

C&E News

Mar 2000

TLC Used As Tool For Combinatorial Synthesis

C&E News

Sept 1999

Combinatorial Chemistry Gains A New Dimension

C&E News

May 1999

MS Technique Facilitates Analysis Of Small Biomolecules

C&E News

May 1999

Bead-Bound Sensors Provide New Approach To Catalyst Discovery

C&E News

March 1999

A Faster Route To New Materials

C&E News

March 1999

Reducing Time To Drug Discovery

C&E News

January 1999

Journal of Combinatorial Chemistry Debuts

C&E News

Dec. 1998

Combinatorial Chemistry Methods Reduce Time and Save Money

C&E News

Sept. 1998

Biosynthesis Combinatorially

C&E News

Apr 27, 1998

Computers customize combinatorial libraries

C&E News

Apr 6, 1998

Combinatorial chemistry

C&E News

Feb 24, 1997

Combinatorial chemistry

C&E News

Feb 12, 1996

Special report on combinatorial chemistry

Argonaut Technologies: Argonaut Technologies, a company that offers semiautomated synthesizer, resins and consumables, host at its web site information related to combinatorial chemistry such as application notes and abstracts. To access this information click here. Argonaut Technologies has online a Resin Selection Guide Chart in PDF format. To download this free chart click here


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Bentham Science Publishers: Bentham Science Publishers publishes the journal 'Combinatorial Chemistry & High Throughput Screening'.

All of Bentham Science's journals published in the year 2000, 2001 and 6 months of 2002 are now available FREE on-line in full text PDF form in collaboration with INGENTA. This unique offer is ONLY available in the year 2003. For more information click here.

Bentham is also offering special journal subscription discounts for a limited period. For more information click here.

Bohdan: See Mettler-Toledo Bohdan.

Bruker Daltonics®: Bruker Daltonics® has online references for LC-MS applications including analysis of combinatorial libraries. The references are available in PDF format. To visit this page click here


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Michel G. R. Calderini: Mr. Calderini has a web page with an illustration depicting how combinatorial chemistry works. To go to Mr. Calderini's website click here.

Center for Solid Phase Organic Combinatorial Chemistry (SPOCC): SPPOC is an educational institution dedicated to general solid-phase combinatorial organic chemistry particularly in drug design of protease inhibitors. SPOCC has a compilation of literature in combinatorial chemistry. To visit this compilation click click here.

Chemical Computing Group Inc. (CCG): The CCG, a company that offers software for combinatorial chemistry, has its online publication Journal of the Chemical Computing Group. To see the current articles click here. To see past articles click here

ChemWeb.com: ChemWeb.com is an online site covering a broad range of topics in chemistry (software, online databases, articles, etc.). To visit this site click here.

Combichem.net: Combichem.net covers a broad line of topics in molecular diversity and combinatorial chemistry.

Combinatorial.com: Combinatorial.com, a member of the Combi-Web Consortium, is the host of the Official Combinatorial Index Website. This site is dedicated to combinatorial chemistry and it is maintained by Dr. Barry A. Bunin, author of the book "The Combinatorial Index". This site provides a vast collection of articles in combinatorial chemistry. To read those articles click here.

Combinatorial Chemistry - an Online Journal: See Elsevier.

Combinatorial Chemistry Network: The Combinatorial Chemistry Network, as part of the Industrial Consortium to support Combinatorial and Solid Phase Chemistry (ICCSP) in the U.K. to promote combinatorial chemistry in UK Universities, has a site online. To visit this site click here.

Combi-Web Consortium: The Combi-Web Consortium brings together the 4 more visited and dedicated sites in the areas of combinatorial chemistry and molecular diversity: 5z.com, Combichem.net, CombiChemLab.com, Combinatorial.com. To visit the Combi-Web portal click here.

ComGenex, Inc.: ComGenex, a company in the business of synthesizing and supplying  drug-like organic molecules, has a web page with information on publications and papers about combinatorial chemistry. To visit this page click here

Current Drug Discovery: Current Drug Discovery, initially part of Current Drugs Lt. and now belonging to The Thomson Corporation, Current Drug Discovery publishes in its June 2002 edition an entire edition dedicated to combinatorial chemistry entitled "Focus on combinatorial chemistry." and it has a free article an online entitled "Whither solid phase synthesis?" To download this article in pdf format click here. To see the summary of then Current Drug Discovery June 2002 issue on line click here.


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Daylight Chemical Information System: Daylight Chemical Information Systems, Inc., provides chemical information processing tools for chemistry. This site hosts a section about combinatorial chemistry. To visit that section click here.

DirectoryScience.com: DirectoryScience.com offers a great compilation of sites relevant to Chemistry, with a section for Organic Chemistry. To visit that section click here.

Drug Discovery and Development (DDD): DDD is a free magazine that covers different aspects of the Pharmaceutical industry, including combinatorial chemistry. For more information about DDD click here.

Drug Discovery Today (DDT): DDT is a journal that covers molecular diversity and drug discovery. DDT includes a section dedicated to combinatorial chemistry. For more information click here.


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Elsevier: Elsevier has available for free the Combinatorial Chemistry - an Online Journal edited by Dr. Nick Terrett:. To access this journal click here.


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Dr. Árpád Furka: Dr. Árpád Furka is considered to be one of the fathers or combinatorial synthesis publishing in 1982 the first split-mix synthesis work in the area of peptide synthesis . Dr. Furka has a website dedicated to combinatorial chemistry covering several historic aspects of combinatorial chemistry, including online links to his origial split-mix synthesis article published in 1982. To visit Dr. Furka's website click here.


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IRORI: IRORI has now available on line an interactive Macromedia Flash demonstration of its "Directed Sorting" process for split-and-pool solid-phase synthesis using radiofrequency-tagged reactors. To see this demo click here


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Journal of Biotechnology and Bioengineering with Combinatorial Chemistry: This journal started its first publication in 1998 and ended publication in 2001. To find information on content and abstracts click here. (NOTE: This journal is discontinued).

Journal of Combinatorial Chemistry: This journal published by the ACS started its first publication in 1998. To access the journal click here.

Journal of Combinatorial Chemistry & High Throughput Screening (CCHTS): This journal, published by Bentham Science Publishers, started its first publication in 1998 covering 2 major fields in drug discovery: Combinatorial Chemistry and High-Throughput Screening (HTS). To find information on content and abstracts click here.


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Mettler-Toledo Bohdan: Mettler-Toledo Bohdan has at its website a list of references and publications for chemistries using its proprietary Miniblock™ Synthesizers and automated synthesizers. To visit this site click here.

Micromass UK Ltd. (Micromass): Micromass has an online  searchable Abstract Database, a Reference Table for mass spec. analysis, and links to other Mass Spectrometry related sites. To access the searchable Abstract Database click here. To access the Reference Table click here. To access other Mass Spectrometry website link page click here.

Milestone Inc.: Milestone Inc. has available at its website free application notes and literature (upon request) for microwave-enhanced synthetic methodologies. To visit this site click here.

Mimotopes: Mimotopes has at his website free online technical information about  solid-phase synthesis and  practical methodologies for its radiofrequency-tagging based and grafted SynPhase™ technologies. To visit this site click here.

Molecular Diversity: Molecular Diversity covers relevant topics related to the areas of combinatorial chemistry and molecular diversity. For more information click here.


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National Institute of Standards and Technology (NIST): The Advanced Technology Program (ATP) at NIST has a website about combinatorial chemistry and materials research. To visit this site click here.

NIST's Advanced Technology Program (ATP) is dedicated to promote the development of innovative technologies for combinatorial chemistry methods applied to materials. To visit ATP's site click here.

Network Science (NetSci): NetSci hosts a section dedicated to combinatorial chemistry (Note: it appears that this section has not been updated since 1996). To visit this section click here.

Novabiochem: Novabiochem has now available online its Novabiochem Letters and Novabiochem Innovation publication series. To access and read these publications online click here.


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Official Combinatorial Index Website: See Combinatorial.com


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Personal Chemistry: Personal Chemistry, a company that offers a microwave-irradiation-driven synthesizer, has on-line examples of protocols used for the synthesis of focused libraries and building blocks in both solid- and solution-phase. To access this site click here

Peptides International: Peptides International has a brief review of classic references in combinatorial chemistry. To see this review click here.

Perkin Transactions 1 (Organic and Bio-organic Chemistry): The Perkin Transaction 1 Journal, published by the Royal Society of Chemistry, includes a compilation of solid-phase organic syntheses at the end of some issues. For more information click here.

Pharmacopeia, Inc.: Pharmacopeia, a company that provides services in the area of informatics, small molecule combinatorial chemistry, and high-throughput screening, has online information about its publications and patents related to combinatorial chemistry. To access its publication information click here. To access its patent information click here.


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Rapp Polymere GmbH: Rapp Polymere, a supplier of polymers, resins and supports, has a section at its site dedicated to some publications related to combinatorial chemistry. To visit this site click here.

Red Optronics: A solution of high quality, affordable, easy-to-use, and versatile Laser Crystals and Optical Components with the latest available technologies applicable to the semiconductor and telecommunication industries. To visit this site click here.

Rolf Claessen's Chemistry Index: Rolf Claessen's Chemistry Index is a site that covers and gives access to databases, journals, books, patents, software, and more. To visit this site click here.


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Sigma-Aldrich: Sigma-Aldrich, a distributor of chemicals, resins and building blocks for combinatorial chemistry synthesis, has an on-line hyperlink to 3 reviews on organic-phase reactions published in the journal Tetrahedron (the reviews are available in PDF format). To visit this site click here. For a list of books on combinatorial chemistry and other related topics click here. For a list of other review articles click here.

Dr. Arno F. Spatola (U. of Louisville): Dr. Arno F. Spatola has an on-line site untitled "What is Combinatorial Chemistry?". To visit Dr. Spatola's site click here.


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Tetrahedron's Combinatorial Chemistry - an Online Journal: See Elsevier.

The Bradley Group: The Bradley Group, a combinatorial chemistry research group led by Prof. Bradley in the U.K., has a site with information about his research and publications. To read about background combinatorial research click here. To access a list of publications click here.

The Ellman Group: Dr. Ellman directs a combinatorial chemistry research group at University of California, Berkeley. His web site contains information about his research and publications. To read about Dr. Ellman's research click here. To read about his publications click here.

The John Nielsen Group: Dr. Nielsen at The Technical University of Denmark has a site dedicated to combinatorial chemistry. It is worth noting that The Technical University of Denmark offers a Ph.D. course in combinatorial chemistry. To visit Dr. Nielsen's site click here.

The Thomson Corporation: See Curren Drug Discovery.


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Waters Corporation: Waters Corporation has online information for LC-MS applications in many areas, including combinatorial chemistry. This site even has a section to do online searches by keywords. Some of the information is found in text format and other in PDF files. To visit this section at Waters Co.'s web site click here.

Wendy Warr & Associates: Wendy Warr & Associates has online information about meetings in different fields, including the area of Combinatorial Chemistry. To visit Wendy Warr's Meeting's sections click here and here.

Dr. Lorenzo Williams (The SINTEF Group): Dr. Lorenzo Williams has on-line a site with information of his work (articles and posters) in combinatorial chemistry with hyperlinks for full access to his material. To visit Dr. William's site click here.