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ANALYTICAL SYSTEMS: POLYMER LABORATORIES

Polymer Laboratories offers its PL-ELS 1000 Evaporative Light Scattering (ELS) Detector for HPLC and LC-MS analysis.

Since the PL-ELS 1000 does not depend of UV detection, any compound can be detected whether it contains a chromophore moiety or not. The PL-ELS 1000 can be used alone or in combination with other type of detectors (UV, Mass Spec, etc.).

The PL-ELS 1000 can be programmed and controlled from either a PC or an IR-based remote control that is mounted on the front of the instrument.

The PL-ELS 1000 operates based on  3 processes:

  • Nebulization of the sample using an inert gas to form uniform droplets.
  • Evaporation of the eluent to form a fine cloud of particles.
  • Optical detection of the particles when disrupting a laser beam.

Since the PL-ELS 1000 can be used with high-throughput LC and LC-MS systems it can aid in the analysis of libraries from combinatorial chemistry.

It is worth mentioning that the PL-ELS 1000 is a sample-destructive analytical method and that to be used with an LC/MS systems they both must use volatile eluent(s).


For more information on the PL-ELS 1000 system click here.

Polymer Laboratories also has a line of chemicals and resins for combinatorial chemistry, peptide synthesis, and scavengers for solution-phase synthesis. To read a review on Polymer Laboratories' chemical products here at CombiChem Lab click here.