BUILDING BLOCKS, LIBRARIES AND RESINS: CHEMNAVIGATOR.COM, INC.

ChemNavigator.com offers its iResearch™ System Library for combinatorial chemistry and high-throughput screening (HTS).

Its iResearch™ System Library contains over 10 million drug-like compounds, the largest available in the world, including 3-D coordinates for all the compounds.

The iResearch™ System Library is offered in several packages:

• The Express Analog Collection with a a minimum purity level of 80%.
• The Lead Expansion 1 Collection with a a minimum purity level of 80%.
• The Lead Expansion 2 Collection with a a minimum purity level of 80%.
• General Collection with a a minimum purity level of 65%.
• Natural Products Collection with a a minimum purity level of 80%.

ChemNavigator.com's on-line site provides 4 different interfaces to draw molecular structures: MDL's Isis/Draw™, Tripos, CambridgeSoft's ChemDraw™, and a new interface from Novartis for the user can choose. The search engine can gather compounds and divide  them in groups from more similar to most diverse subset of compounds. The system allows the user to save queries either at ChemNavigator.com's server or on floppy disks.

ChemNavigator has now available ChemGuide databases covering information such as:

• Active Ingredients from the FDA's approved drug products list.
• Cancer screening data from NCI's cancer-screening program.
• Anti-HIV activity screening data from the NCI Developmental Therapeutics Program.
• GenomeNet Japan's Ligand Database for Enzyme Reactions.
• Patent data from Current Drugs' IDdb3 patent information database. (Note: To obtain full data compound information the user must have a subscription with Current Drugs Ltd.).
• SBI's 3-D protein technology.
• Nanogens Pesticides Database.

For more information on some of these features click here.

For more information on the iResearch™ System Library including product pricing click here.

To see a list of Frequently Asked Questions (FAQ) about ChemNavigator.com click here.