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MICROWAVE
SYSTEMS: CEM CORPORATION
CEM
Corporation offers a comprehensive line of microwave-based
systems for combinatorial synthesis, parallel synthesis, medicinal
chemistry, and scale-up synthesis.
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MARS-S
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For
combinatorial and parallel synthesis CEM offers the MARS-S
microwave synthesis workstation. This workstation can support
many synthesis research needs with a broad throughput by allowing
the use of up to 3 multi-well microtiter plates, 120 16-mm tubes
or 15-ml tubes, 52 30-mm tubes or 50-ml tubes, 100 ml vessels,
and high-pressure 0.5-3 L round bottom flasks. The MARS-S workstation
can control both temperature and pressure up to 1500psi (100
bar), individual reaction vessel stirring. For more information
on the MARS-S microwave synthesis workstation click
here. |
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focus synthesis applications CEM offers its Discover™
system. This synthesizer is a stand-alone synthesis with
a small footprint, and allows the use of -mL up to 125-ml reaction
vessels for reactions done at atmospheric pressures, and the
use of septum-sealed 10-ml vials for high-pressure reaction
conditions (up to 25 bar). The Discover™ system
also controls reaction temperatures, pressures, and stirring
speeds. For more information on the Discover™ system
click
here. |
Discover™
system
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Explorer
PLS™
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To
expedite focus synthesis CEM also offers the automated
version of the Discover™ system: Explorer PLS™
workstation system. This system accommodates up to 4 autosampler
racks each rack holding up to 6 reaction vessels for a throughout
of 24 sequential reactions per cycle, and it provides the
same capabilities found in the Discover™ system.
For
more information on the Explorer PLS™ workstation
system click
here.
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For
higher throughput synthesis CEM also offers
its Navigator™ workstation. This workstation
incorporates an XYZ liquid handling system capable of handling
up to 8 different solvents, and automated weighing station,
and a capping/de-capping station. The Navigator™
workstation can also accommodate multiple Discover™
systems, several 96-position interchangeable racks, and it
can interface with analytical systems (i.e., HPLC, SPE, Flash
chromatography, Raman, etc.).
For
more information on the Navigator™ workstation
click
here.
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Navigator™
workstation
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Odyssey™
Synthesizer
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For
peptide synthesis CEM also has available the Odyssey™
Microwave Peptide Synthesizer.
This
system, also based on CEM's Discover™ system, can accommodate
10 to 100 mL reaction vessels and up to 25 amino acid reservoirs
with a throughput of up to 12 peptides per cycle.
For
more information on the Odyssey™ Microwave Peptide Synthesizer
click
here.
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For
scale-up applications
CEM has the Voyager™ system. This system, also based on the
Discover™ system, can accommodate a 10-mL up to 80-mL reaction
vessel to carry out reactions at atmospheric pressure up to 200°C
or pressures up to 200 psi. CEM also provides 2 different modules
for the
Voyager™ system: the VoyagerCF Continuous Flow module
for solution phase chemistries and the VoyagerSF Stop
Flow module for chemistries that require the use of solid
reagents, highly viscous materials, or are expected to produce insoluble
products.
VoyagerCF
Continuous Flow module
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VoyagerSF
Stop Flow module
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For
more information on the Voyager™ system click
here.
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Investigator™
system
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To
help monitoring and optimizing microwave reactions CEM also
offers the Investigator™ system.
This
system is a Raman-based detector with a small footprint that
works with the Discover™ system allowing real-time reaction
monitoring for reaction development and optimization
For more information on the Investigator™ system click
here.
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