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WORKSTATIONS: ARGONAUT TECHNOLOGIES

Argonaut Technologies offers a broad line of semiautomated synthesizers.

Its Quest™ line includes the Quest™ 205 and Quest™ 210. The first digit in the designation number describes the number of racks and the last 2 digits the number of reaction vessels per rack. So the Quest™ 205 has two 5-fritted tube racks and the Quest™ 210 has two 10-fritted tube racks. In the Quest™ line all vessels are simultaneously vertical-agitated (up-and-down movement) by means of magnetic bars, the Quest™ has capabilities for inert atmosphere as well as heating and cooling conditions, and it comes with an automated solvent wash module.

Quest™ 205 

Quest™ 210

For more information on the Ques™ synthesizers click here.

For information on accessories for the Quest™ synthesizers click here.

FirstMate™

In a similar fashion, Argonaut has a new parallel multichannel synthesizer called FirstMate™. The FirstMate™ line comes in a 206-frame configuration (2 rows of 6 tubes). The FirstMate™ frame can accommodate 2 aluminum blocks each one capable of holding three varieties of glass-made test tubes (13mm x 150mm, 16mm x 150mm, or 25mm x 150 mm) with teflon® caps. As in the Quest line, the FirstMate™ also offers heating and cooling capabilities and vertical agitation.

For more information on the FirstMate™ click here.

 

The Nautilus™ 2400 was the first synthesizer Argonaut Technologies offered to the public. The Nautilus™ 2400 synthesizer holds up to 3 8-vessel racks for the synthesis of up to 24 individual compounds. The Nautilus™ 2400 not only can hold 4 different types of glass-made vessels (5 ml, 8 ml, 15 ml, and 23 ml) with teflon® caps, inlet tubes and frits, but it can also heat and cool (-40 °C to 150 °C) individually each reaction vessel. Mixing is performed by rocking each rack in a 220 degree angle. The Nautilus™ 2400 comes with an autosampler capable of delivering up to 88 reagents to the reaction vessels, and it also comes with a reagent-solvent delivery chamber. Collection of final products is done with the same autosampler. For more information on the Nautilus™ 2400 click here.

Nautilus™ 2400

 

Surveyor™ system

The Surveyor™ system is a more powerful version of the Quest 205. The Surveyor has the 2 5-vessel racks one next to the other (the Quest 205 has the racks one in front of the other). This system offers individual control of reagent and solvent delivery, reaction time and temperature (-40 °C to 140 °C) to each one of the 10 75-ml reaction vessels.

The Surveyor comes with and integrated Hewlett-Packard 1100 HPLC system for unattended on-line sample analysis. The Surveyor also comes with email notification capabilities. For more information on the Surveyor™ system click here.

 

The Endeavor™ system has been designed for material science research. The Endeavor™ holds 8 15-ml reaction vessels offering individual control on temperature (up to 200 °C) and pressure (500 psi) conditions. Mixing in the Endeavor™ is performed using impellers (up to 500 rpm).

For more information on the Endeavor™ system click here.

Endeavor™ system

 

Trident™ synthesizer

The Trident™ synthesizer is the most recent system by Argonaut for high-throughput organic synthesis. The Trident™ holds up to 4 reaction cassettes each cassette holding up to 48 glass-made reaction vessels in a 6 x 8 format to give a maximum throughput of 192 compounds. The Trident™ offers full control of temperature, agitation and solvent/reagent delivery. For smaller throughput Argonaut also offers an agitation-thermal unit that takes 1 reaction cassette with solvent/reagent, agitation and cooling/heating (-40 °C to 150 °C) capabilities.

For more information on the Trident™ synthesizer click here.


Argonaut Technologies also offers a line of resins and reagents for both solution and solid-phase synthesis. For more information about it here at CombiChem Lab click here.