CombiChemLab - News

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NEWS: JULY 2003

-7/31/2003-

MorphoSys AG reaches third milestone in antibody collaboration with Centocor. To read article click here.

FDA approves Schering-Plough Corporation's REBETOL® (ribavirin) for hepatitis C treatment in children. To read article click here.

FDA aprroves Apotex Corp.'s generic version of Paxil. To read article click here.

-7/30/2003-

Waters® Corporation acquires Creon Lab Control for approximately $16 million. To read article click here. Micromass UK Ltd., a division of Waters Corporation, provides mass spectrometer systems for combinatorial chemistry and drug discovery. For a review of Micromass' systems here at CombiChem Lab click here.

Accelrys Inc. will introduce in Fall 2003 Discovery Studio™ Modeling 1.1. To read article click here. Accelrys Inc. provides software packages for molecular modeling, drug discovery, life science, material science, combinatorial chemistry and high-throughput screening. For a review of Accelrys' software packages here at CombiChem Lab click here.

Argonaut Technologies Inc. sells its HPLC business to W.R. Grace & Co. To read article click here. Argonaut Technologies provides chemical and reagents as well as semiautomated synthesizers for parallel synthesis. For a review of Argonaut Technologies' chemicals and semiautomated synthesizers here at CombiChem Lab click here and here, respectively.

Two Wyeth Inc. sales managers settle insider-trading allegations. To read article click here.

ViroPharma Inc.'s drug found to be effective against smallpox in animal tests. To read article click here.

Pfizer to discontinue the development of Phytopharm's P57 for obesity. To read article click here.

-7/29/2003-

Seattle Genetics Inc. and Genencor International Inc. extend cancer research collaboration. To read article click here.

FDA approves Genesoft Pharmaceuticals Inc.'s Factive® (gemifloxacin mesylate) for multi-drug resistant in S. Pneumoniae. To read article click here.

Cubist Pharmaceuticals Inc. receives two SBIR grants for lipopeptide research. To read article click here.

-7/28/2003-

Press Release: SciTegic® Inc. licenses Pipeline Pilot™ to Chiron. To read press release click here.

Seattle Genetics Inc.'s product SGN-30 receives orphan drug designation from the FDA for Hodgkin's disease. To read article click here.

Icogen Corporation receives SBIR grant from the National Institute of Aging (NIA) for Alzheimer's research. To read article click here.

OXiGENE Inc.'s product Combretastatin A4 Prodrug (CA4P) receives orphan drug designation from the FDA for multiple forms of thyroid cancer. To read article click here.

-7/24/2003-

Press Release: Specialist marketing and business development consultancy, Primetek Solutions, have announced STEPWISE™ an export development program for laboratory and process instrumentation companies looking to develop and implement an effective export strategy. To read press release click here.

Discovery Partners International Inc. (DPII) and Bruker AXS Inc. sign multi-year strategic alliance and distribution agreement. To read article click here. DPII has 2 subsidiaries, ChemRx and IRORI, to provide support to drug discovery. ChemRx offers a diverse set of services for combinatorial chemistry and drug discovery. For a review of ChemRx's services here at CombiChem Lab click here. IRORI offers its radio-frequency tagged product line for combinatorial chemistry. For a review on IRORI's Accutag system here at CombiChem Lab click here. Bruker AXS Inc. offers its D8 DISCOVER System for fast X-Ray diffraction screening analysis of combinatorial libraries. For a review on Bruker AXS's D8 DISCOVER System here at CombiChem Lab click here.

FDA approves Baxter International Inc.'s drug Advate for treatment of Hemophilia A. To read article click here.

Diversa Corporation receives NIH grant for antibody research. To read article click here.

-7/24/2003-

IBC to host the "2nd international conference on RNAi" conference on November 3-4, 2003, in Boston, MA. For more information on this conference click here. IBC promotes and hosts a broad range of scientific oriented conferences. For more information on IBC here at CombiChem Lab click here.

Vertex Pharmaceuticals Inc.'s anti-HIV experimental drug 433908 (also known as 908) fails primary goal in clinical trials. To read article click here.

Roche Holding AG to buy Igen International Inc. for about $1.42 billion. To read article click here.

Elan Corp. and Biogen Inc.'s Crohn's drug Antegren fails to meet its Phase III trial's primary endpoints of response. To read article click here.

-7/23/2003-

The San Diego Supercomputing Center licenses GeneGo's MetaCore™ platform for systems biology applications. To read article click here.

GlaxoSmithKline and Shionogi & Co Ltd halt development of anti-HIV 810781 experimental drug. To read article click here.

-7/22/2003-

The Strategic Research Institute (SRI) will host the "Nucleic Acid World Summit" conference on September 15-17, 2003, in Boston, MA. To read article click here. SRI promotes and hosts a broad range of scientific oriented conferences. For more information on SRI here at CombiChem Lab click here.

Applied Biosystems introduces the Applied Biosystems Expression Array System for whole human genome analysis on a single microarray. To read article click here.

Diversa Corporation acquires antifungal program from GlaxoSmithKline. To read article click here.

-7/21/2003-

Press Release: ASINEX Announces One Year Extension to Collaboration with Johnson and Johnson Pharmaceutical Research & Development, a division of Janssen Pharmaceutica N.V (J&JPRD). To read press release click here. ASINEX offers a large collection of highly pure and diverse small organic compounds for CombiChem and HTS as well as its services for chemistry and drug discovery. For a review of ASINEX's compound collections and services here at CombiChem Lab click here.

Pfizer Inc. to support clinical research startup Jasper Clinical Research & Development in Kalamazoo, MI. To read article click here.

Kinexis Inc. and Merck & Co. form CNS research collaboration. To read article click here.

CuraGen Corporation publishes in the journal "Proceedings of the National Academy of Sciences" (PNAS) predictive drug development assay paper entitled "Prediction of Clinical Drug Efficacy by Classification of Drug-Induced Genomic Expression Profiles in vitro." To read article click here.

-7/18/2003-

Press Release: Visitors to the inaugural Lab Automation Europe at Olympia (London, UK) in November will have the chance to see the latest developments in high-throughput solvent removal technology within the new Model HT-24 system from Genevac Ltd. To read press release click here. Genevac Ltd. provides high-throughput centrifugal evaporation systems for combinatorial chemistry, high-throughput screening (HTS) and drug discovery. To read a review of Genevac's systems here at CombiChem Lab click here.

Press Release: Bruker BioSciences Corp.'s latest Investor and Analyst Open House webcast is up and running at Bruker BioSciences Corp.'s website. The full set of 53 slides is easily printable in the Bruker's News & Events section. To access the webcast click here. Bruker AXS Inc. offers its D8 DISCOVER System for fast X-Ray diffraction screening analysis of combinatorial libraries. For a review on Bruker AXS's D8 DISCOVER System here at CombiChem Lab click here. Bruker Daltonics Inc. provides mass spectrometer systems for drug discovery applications. To read a review of Bruker Daltonics' Mass Spec systems here at CombiChem Lab click here.

Press Release: Porvair Sciences Ltd., in conjunction with US partner LabNet International, has announced its presence at the 9th Annual Society for Biomolecular Screening (SBS) meeting in Portland, USA (21-25 September 2003) with the latest additions to its portfolio of specialist microplates and microplate technology for biomolecular screening. To read press release click here.

Therascope AG changes name to Alantos Pharmaceuticals AG. To read article click here.

Undercover videotapes show Abbott Laboratories salespeople influencing a medical-products distributor to allegedly overcharge government insurance programs. To read article click here.

-7/17/2003-

Accelrys releases Discovery Studio™ Accord for Excel. To read article click here. Accelrys Inc. provides software packages for molecular modeling, drug discovery, life science, material science, combinatorial chemistry and high-throughput screening. For a review of Accelrys' software packages here at CombiChem Lab click here.

ArQule Inc. acquires Cyclis Pharmaceuticals Inc. To read article click here. ArQule Inc provides its services for combinatorial chemistry and drug discovery. For a review of ArQule's discovery services here at CombiChem Lab click here.

ZymoGenetics discovers protein CTRP1 is involved in thrombotis. To read article click here.

Researchers at Roche publish in the journal Science new class of drugs (glucokinase activators, GKAs) stimulate the glucose regulating enzyme glucokinase (GK), an enzyme that plays a crucial role in patients with type 2 diabetes. To read article click here.

Entelos Inc. and the Massachusetts Institute of Technology form inflamatory research collaboration. To read article click here.

Compugen Ltd. to transfer its Bioccelerator product line to Biocceleration Ltd. To read article click here.

-7/16/2003-

Press Release: Limited Reimbursements by Third Party Payers Obstruct Sales of Molecular Diagnostic Products. To read press release click here.

Introgen Therapeutics Inc. publishes multiple apoptotic pathways for its anticancer compound INGN 241. To read article click here.

AVI Biopharma Inc. to acquire EXegenics Inc. for about $11 million in stock exchange. To read article click here.

Court rules on favor of Teva Pharmaceutical Industries Ltd. in multi-patent infrigment lawsuit against Ribapharm Inc.'s drug Rebetol. To read article click here.

CellExSys Inc. receives U.S. patent entitled "Hybrid genes for use in the production of TH-independent cytotoxic T cells". To read article click here.

Merck & Co. Inc. and SCYNEXIS Inc. expand and and extend anti-infective multi-year research collaboration. To read article click here.

Biogen Inc., Genzyme Corp., and Abbott Laboratories file lawsuit against Columbia University on gene-splicing technology. To read article click here.

-7/15/2003-

Press Release: Viscotek, the leader in multiple detector characterisation of polymers and proteins, have announced a new technical booklet that explores the principles of measurement and operation of the Low Angle Light Scattering (LALS) Detector. To read press release click here.

Argonaut Technologies Inc. introduces its new Amidation Toolkit. To read article click here. Argonaut Technologies provides chemical and reagents as well as semiautomated synthesizers for parallel synthesis. For a review of Argonaut Technologies' chemicals and semiautomated synthesizers here at CombiChem Lab click here and here, respectively.

Caliper Technologies Corp. completes the acquisition of the Zymark Corporation. To read article click here. Zymark Corporation provides automated systems for combinatorial chemistry and drug discovery. For a review of Zymark's systems for combinatorial chemistry here at CombiChem Lab click here.

FDA approves Eli Lilly & Co.'s drug Zyprexa to be used in combination therapy for bipolar disorders. To read article click here.

VIVUS Inc. receives 2 U.S. patents for female sexual dysfunction: "Methods, Compositions and Kits for Enhancing Female Sexual Desire and Responsiveness," and "Co-Administration of a Prostaglandin and an Androgenic Agent in the Treatment of Female Sexual Dysfunction." To read article click here.

Ribonomics Inc. announces breakthrough using proprietary Systems Biology Pathway Identification in gene identification associated to diabetes. To read article click here.

Boehringer Ingelheim and Medivir form HIV collaboration. To read article click here.

Studies demonstrate potential role of stain drugs in the treatment and prevention of Alzheimer's disease. To read article click here.

Targeted Genetics Corporation and Cystic Fibrosis Foundation Therapeutics (CFFT) begin Phase IIb cystic fibrosis clinical trial of tgAAVCF. To read article click here.

GenVec Inc. receives U.S. patent entitled "Replication Deficient Adenoviral TNF Vector." To read article click here.

4SC and Esteve establish CNS regmgm28search collaboration. To read article click here.

-7/14/2003-

Press Release: The new Model DD-4X centrifugal evaporator from Genevac is an affordable solvent evaporation system that uniquely combines ease of use with uncompromised performance, high sampling versatility and productivity enhancing features. To read press release click here. Genevac Ltd. provides high-throughput centrifugal evaporation systems for combinatorial chemistry, high-throughput screening (HTS) and drug discovery. To read a review of Genevac's systems here at CombiChem Lab click here.

Press Release: Guava Technologies Inc., a biotechnology company providing life science researchers easy-to-use, affordable single cell analysis solutions, today reported record sales growth for the first half of fiscal year 2003. To read press release click here.

Press Release: ESA Analytical, a leading supplier of advanced separations, detection and analysis systems, has announced a new upgrade to its high performance CouloChem III HPLC electrochemical detector. To read press release click here.

Press Release: The FIPA system from Viscotek, leaders in multi-detector characterisation of polymers and proteins, is a fast and simple instrument for providing comprehensive characterisation data for process engineers involved with polymer development. To read press release click here.

CompuCyte Corp. introduces the iCys™ Research Imaging Cytometer. To read article click here.

SRI International receives NCI's R33 grant to develop innovative in vitro assays for liver toxicity. To read article click here.

GlaxoSmithKline and Vertex Pharmaceuticals' HIV protease inhibitor 640385 (VX-385) found active against resistant HIV-1 strands. To read article click here.

ZymoGenetics reports Interleukin 21 (IL-21) supresses tumor growth. To read article click here.

-7/11/2003-

Press Release: Specialists in innovative microplate technology, Porvair Sciences, have announced a range of sterile deep-well plates that provide the ideal medium for storage applications and high yield growth of bacteria, yeast and cell lines. To read press release click here.

BTG moves its non-polyglutamatable thymidylate synthase inhibitor BGC 9331 to phase I/II trials for treatment for gastrointestinal cancers. To read article click here.

Human Genome Sciences Inc. begins development of Trail Receptor-2 antibody for cancer treament. To read article click here.

-7/10/2003-

Press Release: The GelPal from Genetix is a novel, compact benchtop system that effortlessly excises protein spots from both backed and unbacked 1D and 2D polyacrylamide gels and dispenses the removed gel plugs into a 96-well microplate. To read press release click here.

MDL Information Systems Inc. (MDL®) and the FDA sign Cooperative Research and Development Agreement (CRADA) to develop together predictive software modules. To read article click here. MDL provides software and databases for combinatorial chemistry, drug discovery and HTS. For a review of MDL's software for combinatorial chemistry here at CombiChem Lab click here.

ChemNavigator's iResearch™ Library now covers over 10 million compounds. To read article click here. ChemNavigator offers its large compound collection for drug discovery. For a review about ChemNavigator's services here at CombiChem Lab click here.

PanGeo Pharma files for bankruptcy protection. To read article click here.

BioGentech Corp. acquires BioGentec Inc. To read article click here.

Provid Pharmaceuticals Inc. and the BTG form anti-inflammatory small-molecule research collaboration. To read article click here.

ActivX Biosciences Inc. and Pfizer form drug profiling collaboration. To read article click here.

Myriad Genetics Inc. and Mayo Clinic form Alzheimer's drug discovery research collaboration. To read article click here.

-7/09/2003-

Johns Hopkins University acquires production-scale SNP genotyping BeadLab from Illumina Inc. To read article click here.

Biogen Inc.-Idec Pharmaceuticals Inc. merger sealed with a $230 million breakup fee. To read article click here.

Agencourt Bioscience Corporation receives U.S. patent 6,534,262, for the size selective binding of nucleic acids to paramagnetic microparticles. To read article click here.

-7/08/2003-

Press Release: Due for official launch at the forthcoming Drug Discovery meeting in Boston (USA), the aliQuot from Genetix Ltd.is a new purpose built low-volume liquid dispensing system. To read press release click here.

Press Release: Laboratories producing monoclonal antibodies for numerous biological applications using tissue culture flasks or roller bottles are set to benefit from a development by INTEGRA Biosciences. To read press release click here.

IBC to host the "10th Chips to Hits®" conference on October 28-31, 2003, in Boston, MA. For more information on this conference click here. IBC promotes and hosts a broad range of scientific oriented conferences. For more information on IBC here at CombiChem Lab click here.

IBC to host the "2nd Model Organisms in Drug Discovery" conference on August 12-13, 2003, in Boston, MA. For more information on this conference click here. IBC promotes and hosts a broad range of scientific oriented conferences. For more information on IBC here at CombiChem Lab click here.

Merck denies any interest in acquiring Schering-Plough. To read article click here.

Neurion Pharmaceuticals Inc. and Eli Lilly and Company form CNS drug discovery research collaboration. To read article click here.

BioCryst Pharmaceuticals Inc. receives SBIR grant to develop Hepatitis C inhibitors. To read article click here.

Millenium Biologix Inc. and P&G Pharmaceuticals form research collaboration for bone and cartilage diseases. To read article click here.

-7/07/2003-

Press Release: INTEGRA Biosciences has announced the availability of CELLSPIN, a compact system that enables high yield protein expression from mammalian or insect cells growing in suspension. To read press release click here.

Array BioPharma Inc. and GenPath Pharmaceuticals Inc. form oncology research collaboration. To read article click here.

FDA rejects Cellegy Pharmaceuticals Inc.'s NDA for Fortigel 2%. To read article click here.

RNA interference (RNAi) driven companies Alnylam Pharmaceuticals Inc. and Ribopharma AG merge. To read article click here.

Astex Technology and AstraZeneca extend cytochrome P450 research collaboration. To read article click here.

Morphotek Inc. and Novo Nordisk form protein research collaboration. To read article click here.

Teijin Ltd. and Ipsen form development and marketing alliance. To read article click here.

-7/04/2003-

No news today. Independence Day in the USA.

-7/03/2003-

Press Release: Based upon proven robotic pipetting technology, the GenePaint system from Tecan (UK) provides for the automation of the manual steps required for performing in-situ hybridisation of cells or tissues on microscope slides. To read press release click here. Tecan provides the ChemSystem workstation and the TECAN MiniPrep systems for combinatorial chemistry and drug discovery. To read a review of TECAN's systems here at CombiChem Lab click here.

U.S. Federal Trade Commission approves Caliper Technologies Corp.'s acquisition of Zymark Corporation. To read article click here. Zymark Corporation provides automated systems for combinatorial chemistry and drug discovery. For a review of Zymark's systems for combinatorial chemistry here at CombiChem Lab click here.

FDA rejects Eisai Co Ltd.'s Aricept drug for vascular dementia treatment. To read article click here.

Elan Corp. sells rest of Ligand Pharmaceuticals' shares for $65.1 million. To read article click here.

Millennium Pharmaceuticals Inc. and Xenova Group initiate Phase I clinical triala of MLN944 (XR5944) for advanced cancer treatment. To read article click here.

-7/02/2003-

Press Release: Tecan UK has announced the availability of Te-MO 3/3, a multi-channel pipetting option for its Genesis, Freedom and Freedom EVO platforms. Te-MO 3/3 significantly increases the productivity of Tecan robotic workstations without increasing system footprint. To read press release click here. Tecan provides the ChemSystem workstation and the TECAN MiniPrep systems for combinatorial chemistry and drug discovery. To read a review of TECAN's systems here at CombiChem Lab click here.

Bruker Daltonics Inc. and Bruker AXS Inc. complete merger. To read article click here. Bruker AXS Inc. offers its D8 DISCOVER System for fast X-Ray diffraction screening analysis of combinatorial libraries. For a review on Bruker AXS's D8 DISCOVER System here at CombiChem Lab click here. Bruker Daltonics Inc. provides mass spectrometer systems for drug discovery applications. To read a review of Bruker Daltonics' Mass Spec systems here at CombiChem Lab click here.

FDA approves Gilead Sciences' once-daily Emtriva drug for HIV therapy. To read article click here.

Baxter International Inc. to cut 2,500 jobs. To read article click here.

Unofficial rumors mention Amgen Inc. possibly interested in acquiring Abgenix Inc. To read article click here.

Affymetrix Inc. launchs the GeneChip® brand Barley Genome Array. To read article click here.

Invitrogen Corp. to acquire Molecular Probes Inc. for about $325 million. To read article click here.

-7/01/2003-

Argonaut Technologies Inc. introduces its new MP-TsO-TEMPO resin. To read article click here. Argonaut Technologies provides chemical and reagents as well as semiautomated synthesizers for parallel synthesis. For a review of Argonaut Technologies' chemicals and semiautomated synthesizers here at CombiChem Lab click here and here, respectively.

Accelrys Inc. releases Catalyst® 4.8. To read article click here. Accelrys Inc. provides software packages for molecular modeling, drug discovery, life science, material science, combinatorial chemistry and high-throughput screening. For a review of Accelrys' software packages here at CombiChem Lab click here.

ICN Pharmaceuticals Inc. sells its biomedicals division to MP Global Enterprises for about $15 million. To read article click here.

Acusphere Inc. goes public. To read article click here.

Pfizer Inc. to sell Pharmacia's diagnostics business unit. To read article click here.

Targacept Inc. receives SBIR grant to develop computer software to predict small-molecule biological activity. To read article click here.

Provid Pharmaceuticals Inc. and the Duke University Medical Center Division of Neurology form research collaboration for Huntington's disease treatment. To read article click here.