NEWS: JUNE 2003

-6/30/2003-

Discovery Partners Internationa Inc. (DPII) and Seikagaku Corporation form biological screening collaboration. To read article click here. DPII has 2 subsidiaries, ChemRx and IRORI, to provide support to drug discovery. ChemRx offers a diverse set of services for combinatorial chemistry and drug discovery. For a review of ChemRx's services here at CombiChem Lab click here. IRORI offers its radio-frequency tagged product line for combinatorial chemistry. For a review on IRORI's Accutag system here at CombiChem Lab click here.

Johnson & Johnson to pay Millennium Pharmaceuticals up to $750 million to market the anti-cancer drug Velcade™ outside the US. To read article click here.

Syrrx Inc. solves x-ray structure of the c-Kit protein tyrosine kinase. This work will be published in the September issue of the Journal of Biological Chemistry. To read article click here.

FDA approves Corixa Inc.-GlaxoSmithKline's Bexxar® for non-Hodgkin's lymphoma. To read article click here.

ICN Pharmaceuticals Inc. sales its Russian business operations. To read article click here.

-6/27/2003-

ComGenex Inc. to participate in Eurocombi 2. To read article click here. Comgenex Inc. provides services for the synthesis of drug-like compounds for high-throughput screening (HTS) and drug discovery. For a review of Comgenex Inc's services here at CombiChem Lab click here.

Deltagen Inc. files for Chapter 11 for bankruptcy protection. To read article click here.

MDS Pharma Services acquires The Clinical Research Center in New Orleans, Louisiana. To read article click here.

Bayer AG settles 1,042 Baycol-related lawsuits out of court for $343 million. Other 9,400 cases are still pending. To read article click here.

-6/26/2003-

Tripos Inc. and ChanTest from collaboration to develop predictive hERG ion channel model. To read article click here. Tripos Inc. provides software and services for combinatorial chemistry and drug discovery. For a review of Tripo's software and services here at CombiChem Lab click here and here, respectively.

FDA gives Genentech Inc.'s anti-cancer drug Avastin fast track status. To read article click here.

Pfizer Inc.'s experimental combination therapy for malaria found to be 96% effective. To read article click here.

Elan Pharmaceuticals misses deadline resulting in a 30% dive of its stock. To read article click here.

Adherex Technologies Inc. receives US patent covering proprietary methods for killing tumor cells using a cadherin compound class. To read article click here.

Elitra Pharmaceuticals names Paul Hamelin CEO. To read article click here.

FDA gives GlaxoSmithKline and Biovail Corp. approvable letter for antidepressant Wellbutrin XL™. To read article click here.

Researchers at Myogen Inc. and the University of Texas Southwestern Medical Center at Dallas announce the use histone deacetylase (HDAC) inhibitors for cardiac applications. To read article click here.

Schering AG linceses antibody-based therapeutic fusion protein from Philogen. To read article click here.

-6/25/2003-

SciTegic® Inc. and MDL Information Systems Inc. (MDL®) incorporate SciTegic's PipelinePilot™ into MDL's suite of cheminformatics programs. To read article click here. MDL provides software and databases for combinatorial chemistry, drug discovery and HTS. For a review of MDL's software for combinatorial chemistry here at CombiChem Lab click here.

Ciphergen Biosystems Inc. opens new Process Proteomics Center near Boston, MA. To read article click here.

Aventis SA files for US approval for insulin glulisine injection. To read article click here.

Entropin Inc. to be delisted from Nasdaq. To read article click here.

Roche launches its new AmpliChip CYP450 microarray system for polymorphism detection and analysis of CYP2D6 and CYP2C19. To read article click here.

Evotec OAI and Axxima Pharmaceuticals AG sign small molecule collaboration agreement centering on Axxima's kinase targets. To read article click here.

FDA clears Human Genome Sciences Inc.'s anthrax drug for human testing. To read article click here.

-6/24/2003-

Press Release: ESA Laboratory Services has developed a highly specific, sensitive, interference-free, and accurate HPLC method using proprietary multi-channel electrochemical array detection technology in conjunction with an automated column switching procedure to measure 8-hydroxy-2'-deoxyguanosine (8OH2'dG) in urine - a prime indicator of oxidative DNA damage. To read press release click here.

Press Release: Guava Technologies' has announced that Life Science researchers can accelerate their research by detecting cell health earlier using their unique ViaCount assay. To read press release click here.

Argonaut Technologies Inc. introduces the Argonaut Bioanalytical Toolbox for ADMET sample preparation. To read article click here. Argonaut Technologies provides chemical and reagents as well as semiautomated synthesizers for parallel synthesis. For a review of Argonaut Technologies' chemicals and semiautomated synthesizers here at CombiChem Lab click here and here, respectively.

Genzyme Corp. and Dyax Corp.'s form joint venture on Dyax's DX-88 protease inhibitor for hereditary angioedema treatment. To read article click here. Biotage Inc., a division of Dyax Corp., has a broad variety of purification systems for drug discovery. To find a review of Biotage's purification systems here at CombiChem Lab click here.

Agilent Technologies Inc. and Dharmacon Inc.form RNA interference research collaboration. To read article click here. Agilent Technologies provides high-throughput HPLC analytical systems for combinatorial chemistry and drug discovery. For a review of Agilent's analytical systems here at CombiChem Lab click here.

Merck's Medco unit faces fraud claims. To read article click here.

Advanced Life Sciences receives SBIR grant for proteomics-based technology targeting protein-aggregation based diseases. To read article click here.

ZymoGenetics Inc. to invest $17 million to expand its facilities in a 68,000-square-foot project. To read article click here.

The National Cancer Institute (NCI) and Introgen Therapeutics Inc. form collaboration to co-develop Introgen's p53 based cancer agent Advexin. To read article click here.

Applied Molecular Evolution Inc. and Eli Lilly and Co. form research collaboration for the optimization of protein therapeutics. To read article click here.

Aventis chooses Caliper Technologies Corp.'s Caliper 250 drug discovery system to develop kinase screening assays. To read article click here.

BioSeek Inc. and Dynavax Technologies from collaboration to profile Dynavax's thiazolopyrimidine-based compounds in cell-based model systems for treatment of chronic inflammatory diseases. To read article click here.

Gilead Sciences Inc. and Bukwang Pharm. Ind. Co. terminate collaboration on chronic hepatitis B experimental drug clevudine. To read article click here.

Isis Pharmaceutcials Inc. and ITRI of Taiwan form SARS antisense drug discovery collaboration. To read article click here.

BioAdvance launche the Greater Philadelphia Bioinformatics Alliance. To read article click here.

-6/23/2003-

Millipore Corporation and Applied Biosystems introduce the MALDIspot™ Kit. To read article click here. Applied Biosystems/MDS Sciex provides mass spectrometer systems for combinatorial chemistry and drug discovery. For a review of Applied Biosystems/MDS Sciex's systems here at CombiChem Lab click here.

Agilent Technologies Inc. introduces the Agilent Human 1B Oligo Microarray Kit for gene expression analysis. To read article click here. Agilent Technologies provides high-throughput HPLC analytical systems for combinatorial chemistry and drug discovery. For a review of Agilent's analytical systems here at CombiChem Lab click here.

Inpharmatica Ltd to acquire some ArQule Inc.'s assets including ArQule's laboratories in Cambridge, MA, as well as certain intellectual property. Fifteen of ArQule former staff will join Inpharmatica following the deal. To read article click here. ArQule Inc provides its services for combinatorial chemistry and drug discovery. For a review of ArQule's discovery services here at CombiChem Lab click here.

LION bioscience launches the LION Target Engine™. To read article click here. LION offers its iDiscovery™ technologies and services for drug discovery. For a review of Lion's services here at CombiChem Lab click here.

Biogen and IDEC Pharmaceuticals announce $6.4 billion all-stock deal merger. To read article click here.

Incyte Corporation and Point Technologies Inc. sign multi-patent licensing agreement. To read article click here.

Affymax Inc. names Arlene M. Morris President and CEO. To read article click here.

Ribapharm Inc. rejects ICN Pharmaceuticals Inc.'s unsolicited offer to buy back 20% of the company. To read article click here.

Cadus Pharmaceutical Corp. changes its name to Cadus Corporation. To read article click here.

MDS Pharma Services expands its biopharmaceutical capabilities. To read article click here.

FDA finds Amgen Inc.'s rheumatoid arthritis drug Enbrel to be effective for treating a type of spinal arthritis. To read article click here.

Gene Logic Inc. launches its new gene expression solution ASCENTA™ System. To read article click here.

FDA approves Barr Laboratories Inc.'s generic version of anti-seizure drug Dilantin. To read article click here.

Biosyn Inc. files Investigational New Drug (IND) application to the FDA for the development of UC-781 as an HIV microbicide. To read article click here.

Morphotek Inc. receives US patent 6,576,468 for the isolation of mutant cell lines to generate novel antimicrobial agents. To read article click here.

-6/20/2003-

FDA approves the injectable antibody-based drug Xolair® for asthma. To read article click here.

FDA approves Bristol-Myers Squibb Co.'s drug Reyataz™ for HIV. To read article click here.

FDA approves PRILOSEC® (omeprazole) for sale over-the-counter for heartburn treatment. To read article click here.

Genentech Inc. and IDEC Pharmaceuticals Corp. to develop humanized anti-CD20 antibodies to target B-cell disorders. To read article click here.

AstraZeneca PLC pleads guilty to violating a federal drug-marketing law related to its Zoladex prostate cancer drug and agrees to pay a $354.9 million fine. To read article click here.

Degussa AG to buy out Cargill. To read article click here.

-6/19/2003-

ArQule Inc.'s small molecule p38 MAP kinase inhibitor shows oral activity in a rat model of rheumatoid arthritis. To read article click here. ArQule Inc provides its services for combinatorial chemistry and drug discovery. For a review of ArQule's discovery services here at CombiChem Lab click here.

Diabetes patients sue GlaxoSmithKline Plc for not disclosing serious side effects of the insulin drug Avandia. To read article click here.

Martha Stewart trial set for January 12, 2004. To read article click here.

Forest Laboratories Inc.'s therapy of memantine and acetylcholinesterase inhibitors for the treatment of mild to moderate Alzheimer's disease did not provide the significat expected effect. To read article click here.

MacroChem Corp. names Robert J. DeLuccia president and CEO. To read article click here.

Drug combination of Johnson & Johnson and Schering-Plough Corp.'s drug Remicade with standard rheumatoid arthritis treatment prevents joint damage. To read article click here.

CuraGen Corp. to cut roughly 20% of its work force. To read article click here.

Molecular Insight Pharmaceuticals Inc. names David S. Barlow chairman and CEO. To read article click here.

-6/18/2003-

Press Release: The new EZ-2 for workgroups centrifugal evaporator from Genevac brings the benefits of leading edge solvent evaporation technology to small groups of scientists working in medicinal chemistry and drug discovery laboratories. To read press release click here. Genevac Ltd. provides high-throughput centrifugal evaporation systems for combinatorial chemistry, high-throughput screening (HTS) and drug discovery. To read a review of Genevac's systems here at CombiChem Lab click here.

Press Release: INTEGRA Biosciences has announced the launch of the PIPETBOY Comfort Colour range, personalised pipettes designed to combine leading-edge user comfort with fast, precise liquid dispensing. To read press release click here.

Tripos Inc. and NOVASCREEN Biosciences Corporation sign mutual service and distribution agreement. To read article click here. Tripos Inc. provides software and services for combinatorial chemistry and drug discovery. For a review of Tripo's software and services here at CombiChem Lab click here and here, respectively.

GlaxoSmithKline PLC installs robotics systems at a plant near Madrid to boost drug discovery. To read article click here.

Amarin Corporation plc and ACADIA Pharmaceuticals sign development agreement centering around ACADIA's small molecule ACP-103, a drug candidate for the treatment of neuropsychiatric and neurological disorders. To read article click here.

Exelixis Inc. moves its proprietary small molecule anticancer compound XL784 to Phase I clinical trials. To read article click here.

-6/17/2003-

Press Release: Benefiting from a state-of-the-art optical system and new software the next generation aQuire confocal scanner from Genetix provides simple and rapid high-resolution imaging of microarrays. To read press release click here.

IBC will host the "Biomarkers in Drug Discovery", the "8th annual World Congress Drug Discovery Technology™", and the "2nd Annual Model Organisms in Drug Discovery" conferences on August 12-13, 2003, in Boston, MA. For more information on this conference click here. IBC promotes and hosts a broad range of scientific oriented conferences. For more information on IBC here at CombiChem Lab click here.

Former Rite Aid Corp. CEO Martin Grass pleads guilty to fraud. To read article click here.

FDA approves MedImmune Inc.'s nasal spray flu vaccine FluMist™. To read article click here.

Cell Therapeutics Inc. to acquire Novuspharma for around $236 million. To read article click here.

Dr. Thomas D. Ingolia joins Myriad Proteomics Inc. as President and CEO. To read article click here.

Bio-Technology General Corp. changes its name to Savient Pharmaceuticals Inc. To read article click here.

Genentech Inc. and Biogen Inc. form research collaboration focusing on the BR3 protein for rhuematoid arthritis and lupus treatment. To read article click here.

Angiogenix Inc. names Edmon R. Jennings as President and CEO. To read article click here.

European Union approves Eli Lilly and Co.'s new osteoporosis drug Forteo. To read article click here.

-6/16/2003-

Press Release: New collaborative research between scientists at the Institut Jean Godinot in Reims, France and Guava Technologies, Inc. demonstrates the superiority of micro capillary cytometry technology over standard microscopic methods for monitoring dendritic cells for research and therapeutic applications. To read press release click here.

Gut hormones shown to affect obesity and diabetes. To read article click here.

Amylin Pharmaceuticals Inc. submits New Drug Application (NDA) for SYMLIN® (pramlintide acetate) for the treatment of diabetes. To read article click here.

Cytogen Corp. to reacquire the rights to Quadramet® from Berlex Laboratories. To read article click here.

Gene Logic Inc. launches Genesis Enterprise System™ 2.0. To read article click here.

La Jolla Pharmaceutical Co.'s experimental drug Riquent™ for lupus treatment fails Phase 3 clinical trials. To read article click here.

Novartis Pharma in-licenses Compugen Ltd.'s Leads computational biology platform for identification, prioritization and validation of new drug targets for 1 more year. To read article click here.

-6/13/2003-

Press Release: Rapid drying with no loss of sample and no cross-contamination due to solvent bumping is provided by the unique Dri-Pure™ technology designed for use with Genevac centrifugal solvent evaporators. To read press release click here. Genevac Ltd. provides high-throughput centrifugal evaporation systems for combinatorial chemistry, high-throughput screening (HTS) and drug discovery. To read a review of Genevac's systems here at CombiChem Lab click here.

King Pharmaceuticals Inc. completes the acquisition of two drugs from Elan Corp for $750 million. To read article click here.

Biokeys Pharmaceuticals Inc. changes its name to ADVENTRX Pharmaceuticals Inc. To read article click here.

-6/12/2003-

Press Release: Viscotek Europe, the leader in multiple detection characterisation of synthetic and natural polymers, has announced an expansion of its analytical services business. To read press release click here.

Press Release: Viscotek Europe represents further copies of reviews of applications notes forwarded to the international trade press over the last 6 months. To read press release click here.

Press Release: The new p3 from Porvair Sciences incorporates a novel dual filter design that eliminates the sample breakthrough and waste associated with leakages from traditional protein precipitation microplates. To read press release click here.

OSI Pharmaceuticals Inc. completes the acquisition of Cell Pathways Inc. To read article click here.

Callisto Pharmaceuticals and the National Cancer Institute (NCI) form collaboration to develop Atiprimod for colon cancer treatment. To read article click here.

Dharmacon Inc. and Exelixis Inc. from collaboration to develop as interfering RNA (siRNA) library againts 600 genes for kinases and other drug discovery targets. To read article click here.

Genetronics Biomedical Corp. receives 2 U.S. patents entitled "Method of Treatment Using Electroporation Mediated Delivery of Drugs and Genes" and "Needle Electrodes for Mediated Delivery of Drugs and Genes." To read article click here.

CombinatoRx Inc. publishes in the June 24th 2003 edition of the Proceedings of the National Academy of Sciences systematic approach to the discovery of multicomponent therapeutics. To read article click here.

Illumina Inc. launches its Sentrix BeadChip platform. To read article click here.

Replidyne Inc. acquires rights to novel antibacterial program from GlaxoSmithKline. To read article click here.

-6/11/2003-

Press Release: ESA and Picometrics have introduced the ZETALIF Evolution a new laser induced fluorescence detector offering sensitivity typically 100-1,000 times that of conventional fluorescence detection. To read press release click here.

Press Release: Porvair Sciences, specialists in innovative microplate technology, have announced new additions to their comprehensive range of Krystal clear-bottomed microplates. To read press release click here.

New Cambridge Healthtech Institute (CHI) Insights report: "GPCRs: Mining the Richest Vein in Drug Discovery." To read article click here. CHI promotes and hosts a broad range of scientific oriented conferences. For more information on CHI here at CombiChem Lab click here.

Argenta Discovery Ltd. and the Japanese pharmaceutical company Teijin from lead optimization collaboration. To read article click here.

Medarex Inc. initiates Phase I clinical trial of its ully human anti-CTLA-4 antibody MDX-010 for HIV treatment. To read article click here.

Vyrex Corporation receives U.S. patent 6,541,613 entitled "Isoflavone Derivatives." To read article click here.

Genta begins new clinical trial of its lead anticancer drug Genasense™ (oblimersen sodium) for advanced breast cancer treatment. To read article click here.

Adherex Technologies Inc. receives U.S. patent covering inhibition of intracellular catenin molecules for cancer treatment. To read article click here.

Orchid BioSciences Inc. avoids Nasdaq deslisting. To read article click here.

Onyx Pharmaceuticals Inc. discontinues virus program and cuts 50 jobs to focus on RAF small-molecule kinase inhibitor BAY 43-9006. To read article click here.

Curis Inc. and Genentech form cancer alliance. To read article click here.

-6/10/2003-

Press Release: Genetix have announced that their QBot or QPix2 colony pickers can be used in conjunction with Templiphi, a novel isothermal DNA amplification method developed by Amersham Biosciences, for swift, efficient sequence identity. To read press release click here.

Former ImClone Systems Inc.'s founder and CEO Samuel Waksal sentenced to 87 months in prison and ordered to pay $3 million in fines. To read article click here.

Cell Pathways' stockholders approve merger with OSI Pharmaceuticals. To read article click here.

Vertex Pharmaceuticals Inc. to cut 111 jobs (13 % ) of its work force involved in early discovery programs. To read article click here.

Genaera Corporation receives U.S. patent 6,576,434 entitled "Methods for Identification of Agents which Modulate Chloride Channel Activity." To read article click here.

BioSeek Inc. receives NIH Grant to develop High-Throughput Human Cell Systems for compound screening. To read article click here.

Curis Inc. receives U.S. patent 6,576,237 entitled "Vertebrate Pattern Inducing Proteins, and Uses Related Thereto." To read article click here.

Regeneron Pharmaceuticals Inc.'s "VEGF- Trap" shrinks kidney tumors and lung micrometastases in mice study. To read article click here.

CalbaTech Inc. acquires MolecularWare Inc. To read article click here.

Barr Laboratories Inc. buys rights for four products from Wyeth. To read article click here.

Ceapro Inc. names Dr. Mark Redmond as President and CEO. To read article click here.

-6/09/2003-

Press Release: Designed for researchers who need to carry out a modest number of experiments per run, the new, fully automated HS 400 Hybridisation Station from Tecan (UK) significantly improves the reproducibility of microarray results. To read press release click here. Tecan provides the ChemSystem workstation and the TECAN MiniPrep systems for combinatorial chemistry and drug discovery. To read a review of TECAN's systems here at CombiChem Lab click here.

Press Release: Available from SensIR Europe, a company dedicated to simplicity in spectroscopic & microscopic sampling, are a range of Video Demonstration CD's providing customers with all of the information required to evaluate their products anywhere, anytime. To read press release click here.

Caliper Technologies Corp. to acquire Zymark Corp. for about $71 million. To read article click here. Zymark Corporation provides automated systems for combinatorial chemistry and drug discovery. For a review of Zymark's systems for combinatorial chemistry here at CombiChem Lab click here.

Amylin Pharmaceuticals Inc. names Ginger L. Graham President and CEO. To read article click here.

Zyomyx Inc. names Robert Monaghan CEO. To read article click here.

MedImmune Inc. and Micromet AG form collaboration to develop Micromet AG's B cell tumor drug MT103. To read article click here.

-6/05/2003-

Press Release: The Strategic Research Institute's Structure-Based Drug Design Conference to take Place on June 23-24, 2003, in San Francisco, CA. To read press release click here. The Strategic Research Institute (SRI) promotes and hosts a broad range of scientific oriented conferences. For more information on SRI here at CombiChem Lab click here.

Press Release: Tecan UK, a leading player in the Life Sciences supply industry, today announced the release of Gemini 4.1 and Magellan Tracker 4.0. These new software solutions have been designed for customers who need to meet the FDA's 21 CFR Part 11 Regulations. To read press release click here. Tecan provides the ChemSystem workstation and the TECAN MiniPrep systems for combinatorial chemistry and drug discovery. To read a review of TECAN's systems here at CombiChem Lab click here.

Acuity Pharmaceuticals moves into the Science Center. To read article click here.

Paradigm Genetics Inc. avoids Nasdaq deslisting. To read article click here.

Icos Corp. and Biogen Inc. terminate psoriasis research collaboration. To read article click here.

-6/05/2003-

Applied Biosystems introduces its new 4700 Proteomics Discovery System. To read article click here. Applied Biosystems/MDS Sciex provides mass spectrometer systems for combinatorial chemistry and drug discovery. For a review of Applied Biosystems/MDS Sciex's systems here at CombiChem Lab click here.

Applied Biosystems introduces its new Linear Ion Trap Mass Spectrometer for pharmaceutical and proteomics research. To read article click here. Applied Biosystems/MDS Sciex provides mass spectrometer systems for combinatorial chemistry and drug discovery. For a review of Applied Biosystems/MDS Sciex's systems here at CombiChem Lab click here.

Millennium Pharmaceuticals Inc. to lay off 600 employees and close two facilities. To read article click here.

Negotiation talks between Amgen Inc. and Tularik Inc. for possible business combination brake off. To read article click here.

Imclone and Bristol-Myers Squibb to seek approval for anti cancer drug Erbitux in 2nd half of 2003. To read article click here.

Rite Aid Corp.'s ex-CFO Frank Bergonzi pleads guilty to fraud conspiracy. To read article click here.

Antares Pharma Inc. receives delisting notice from Nasdaq. To read article click here.

Inflazyme Pharmaceuticals Ltd. completes the acquisition of GlycoDesign Inc. To read article click here.

Genteric Inc. names Dr. Mitchell H. Finer, Ph.D., as President and CEO. To read article click here.

Eli Lilly and Company, the World Health Organization, the U.S. Department of Health and Human Services' Centers for Disease Control and Prevention, Brigham and Women's Hospital, and Purdue University join efforts to treat Multi-Drug Resistant Tuberculosis. To read article click here.

The Kucera Pharmaceutical Company receives SBIR grant for its R&D efforts on its anti-HIV compound KPC-2. To read article click here.

Nature Technology Corporation receives U.S. patent 6,573,091 for a novel type of gene therapy vector technology. To read article click here.

Caliper Technologies Corp. and Bio-Rad Laboratories form alliance to develop a new microfluidics LabChip®. To read article click here.

-6/04/2003-

Martha Stewart charged with securities fraud. She steps down as chairman and CEO of Martha Stewart Living Omnimedia Inc. To read article click here.

NPS Pharmaceuticals Inc. and Enzon Pharmaceuticals Inc. cancel merger. To read article click here.

Ligand Pharmaceuticals and GlaxoSmithKline to continue Phase I development of 501516 targeting the peroxisome proliferation activated receptor (PPAR) modulator for the treatment of dyslipidemias. To read article click here.

BioSante Pharmaceuticals Inc. to deveop biodefense vaccines for the U.S. Army's Medical Research Institute of Infectious Diseases (USAMRIID). To read article click here.

Pintex Pharmaceuticals submits patent application for enzyme Pin1 inhibition. Pin1 is associated to numerous cancers and neurodegenerative diseases including Alzheimer's. To read article click here.

SCYNEXIS Europe Ltd. and Molecular Engines Laboratories form anti-cancer research collaboration. To read article click here.

FDA gives "fast-track" status to Oxigene Inc.'s drug to treat rare form of thyroid cancer. To read article click here.

-6/03/2003-

Press Release: Using a minimal number of cells, the Guava Cell Cycle Assay enables researchers to rapidly screen drug compounds or explore key pathways controlling cell growth and death. To read press release click here.

Press Release: Opportunities In The European Proteomics Mass Spectrometry Markets - A New Study By Frost & Sullivan. To read press release click here.

MDS Sciex and Eksigent Technologies sign marketing agreement. To read article click here. Applied Biosystems/MDS Sciex provides mass spectrometer systems for combinatorial chemistry and drug discovery. For a review of Applied Biosystems/MDS Sciex's systems here at CombiChem Lab click here.

Cambridge Healthtech Institute (CHI) releases new report: Advances in Lead Optimization Accelerating Drug Discovery and Development. To read article click here. CHI promotes and hosts a broad range of scientific oriented conferences. For more information on CHI here at CombiChem Lab click here.

Lion Bioscience and Silicon Genetics sign development and marketing collaboration to integrate Silicon Genetics' GeneSpring software and Lion's SRS platform. To read article click here. LION offers its iDiscovery™ technologies and services for drug discovery. For a review of Lion's services here at CombiChem Lab click here.

President and CEO of Elite Pharmaceuticals resigns. To read article click here.

Cell nuclei transfer of brain cancer cells into mouse eggs produces cancer-free cloned embryos. To read article click here.

Demegen Inc. and Dow Pharmaceutical Sciences form collaboration to develop selected Demegen peptides. To read article click here.

CombiMatrix Corporation launches siRNA-based drug discovery program: CombiMatrix's Express Track(sm). To read article click here.

RxKinetix Inc. acquires exclusive rights to RK-0202 for oral mucositis. To read article click here.

Meyer Pharmaceuticals LLC receives 2 U.S. patents 6,569,664 and 6,573,062 for TNF Receptor Releasing Enzyme. To read article click here.

-6/02/2003-

Press Release: The IlluminatIR™ from SensIR Europe is a unique system that transforms an infinity-corrected light microscope into a versatile infrared microprobe. To read press release click here.

Actelion Ltd and Discovery Partners International Inc. (DPII) to form 3-year collaboration. To read article click here. DPII has 2 subsidiaries, ChemRx and IRORI, to provide support to drug discovery. ChemRx offers a diverse set of services for combinatorial chemistry and drug discovery. For a review of ChemRx's services here at CombiChem Lab click here. IRORI offers its radio-frequency tagged product line for combinatorial chemistry. For a review on IRORI's Accutag system here at CombiChem Lab click here.

Axonyx Inc. begins clinical trials of Phenserine for Alzheimer's Disease (AD). To read article click here.

ICN Pharmaceuticals Inc. offers $168 million bid to acquire 20% stake in Ribapharm Inc. To read article click here.

Antigenics Inc's AG-858 cancer vaccine provides positive results in combination with Novartis AG drug Gleevec (Glivec, STI571). To read article click here.

Protein Design Labs initiates clinical trials of Anti-a5B1 integrin antibody in solid tumors. To read article click here.

Axon Instruments Inc. and CSIRO complete neuronal image analysis collaboration for the monitoring of neural growth. To read article click here.

ImClone Systems Inc. reports positive data on its experimental cancer drug Erbitux. To read article click here.

Deadline to apply for GlaxoSmithKline's Drug Discovery and Development Research Grant Program for HIV/AIDS extended to July 31, 2003. To read article click here.

Neuro Bioscience Inc. completes the acquisition of CLL Pharma S.A. To read article click here.

Neuro Bioscience Inc. appoint Edward W. Kelly as President and CEO. To read article click here.

Bayer AG's Raf kinase inhibitor BAY 43-9006 shows early signs of tolerability and activity in 3 different antitumor clinical trials. To read article click here.

Ciphergen Biosystems Inc. launches its new Interaction Discovery Mapping platform based on the SELDI ProteinChip Biomarker System. To read article click here.

7 Directors resign from Oxford Glycosciences. To read article click here.

Corixa Corporation begins Phase I clinical trials of HER-2/neu vaccine for breast cancer treatment. To read article click here.