NEWS: MAY 2003

-5/30/2003-

The Food and Drug Administration (FDA) and the National Cancer Institute (NCI) form joint program to expedite cancer drug development. To read article click here.

Cellomics Inc. and Carl Zeiss MicroImaging Inc. form distribution and service alliance. To read article click here.

MacroChem Corp. to be deslisted from NASDAQ on June 6, 2003. To read article click here.

Ariad Pharmaceuticals' lead anti-cancer compound AP23573 found "highly effective" in animal models. To read article click here.

Genaera Corporation and the National Cancer Institute (NCI) form collaboration to evaluate second generation of anti-angiogenic aminosterol compounds. To read article click here.

Merck KGaA stops diabetes research program. To read article click here.

BioTrove Inc. names Robert H. Ellis as CEO. To read article click here.

Orchid BioSciences Inc. cuts jobs in its Orchid GeneShield unit. To read article click here.

Invitrogen Corp. hires Gregory T. Lucier as president & CEO. To read article click here.

FDA committee gives thumbs up to Sanofi-Synthelabo's drug Alfuzosin to treat heart irregularity. To read article click here.

-5/29/2003-

Press Release: Previewed last week at Achema 2003, the advanced prototype of the HT-24 high-throughput solvent removal system from Genevac Ltd generated considerable interest from visitors particularly those involved with drug discovery and purification. To read press release click here. Genevac Ltd. provides high-throughput centrifugal evaporation systems for combinatorial chemistry, high-throughput screening (HTS) and drug discovery. To read a review of Genevac's systems here at CombiChem Lab click here.

Press Release: Guava Technologies Inc announces a proprietary method that improves the productivity and substantially reduces the labour costs associated with automated cell counting and viability determination. To read press release click here.

The Center for Business Intelligence (CBI) announce upcoming conferences in its Pharmaceutical Conference Series in 2003. To read article click here. CBI organizes and hosts a series of conferences in the pharmaceutical areas. For more information on CBI here at CombiChem Lab click here.

Current Drugs launchs the Strategic Drugs database (SDdb). To read article click here.

Hugh Grant becomes president and CEO of Monsanto Co. To read article click here.

GlycoDesign Inc. shareholders approve the acquisition of Inflazyme Pharmaceuticals Ltd. To read article click here.

Allos Therapeutics Inc. to cut 30 percent of its work force. To read article click here.

Allos Therapeutics Inc. to submit New Drug Application (NDA) to the FDA for RSR13 (efaproxiral) to treat brain metastases from breast cancer. To read article click here.

Dharmacon Inc. launches the SARS siARRAY™ Gene Set. To read article click here.

DrugMax Inc. acquires the assets of Avery Pharmaceuticals Inc. To read article click here.

Isis Pharmaceuticals Inc. initiates Phase II clinical trial of ISIS 14803 for hepatitis C virus (HCV). To read article click here.

Pain Therapeutics Inc.'s drug PTI-901 significantly improves all the common symptoms associated with Irritable Bowel Syndrome (IBS). To read article click here.

-5/28/2003-

Elsevier and MDL to create new Life Sciences division. To read article click here. MDL provides software and databases for combinatorial chemistry, drug discovery and HTS. For a review of MDL's software for combinatorial chemistry here at CombiChem Lab click here. Elsevier also has a free online journal dedicated to combinatorial chemistry. For more information on this journal here at CombiChem Lab click here.

Merck & Co. files SEC documents for spin off of Medco Health Solutions Inc. To read article click here.

Echelon Biosciences Inc. receives $600,000 grant from NIH entitled "Liposome Overlays for Protein -- Ligand Selectivity". To read article click here.

GlaxoSmithKline Inc. licenses Corixa Corp.'s Bexxar cancer therapy rights to market it in Canada. To read article click here.

Epoch Biosciences Inc. to sell its specialty oligonucleotide operations in San Diego, California, to Eurogentec S.A. To read article click here.

Proteome Systems Ltd and Iberica Co. form proteomics and glycomics research collaboration for osteoarthritis treatment. To read article click here.

CombinatoRx Inc. receives U.S. patent 6,569,853 covering one of its anti-cancer drug candidates that induces apoptosis in tumor cells. To read article click here.

Wyeth extends subscription to Gene Logic Inc.'s BioExpress System. To read article click here.

Orchid BioSciences Inc. names Paul J. Kelly as CEO. To read article click here.

-5/27/2003-

The Strategic Research Institute (SRI) will host the "International Psychiatric Drug Discovery & Development" conference on June 23-24, 2003, in Princeton, NJ. To read article click here. SRI promotes and hosts a broad range of scientific oriented conferences. For more information on SRI here at CombiChem Lab click here.

More than 70 abstracts on Gleevec (Glivec, STI571) to be presented at the annual meeting of the American Society of Clinical Oncology in Chicago. To read article click here.

European Commission approves Roche Holding AG's Fuzeon™ for HIV treatment. To read article click here.

SIRTeX Medical Ltd.'s shareholders turn down Cephalon Inc.'s $161 million takeover bid. To read article click here.

FDA gives VaxGen Inc. OK to initiate Phase I clinical trials of anthrax vaccine candidate. To read article click here.

Immtech International Inc. initiates Phase IIb human clinical trial of its oral drug DB289 for the treatment of Pneumocystis carinii pneumonia. To read article click here.

BioForce Nanosciences Inc. receives Nanoarray patent entitled "Method and Apparatus for Solid State Molecular Analysis." To read article click here.

IVAX Corporation to acquire the inhalation technology company Advanced Tobacco Products Inc. To read article click here.

Ingenuity Systems launches the world's largest curated database of biological networks: the Ingenuity Pathways Knowledge Base. To read article click here.

Nymox Pharmaceutical Corp. creates new drug for Alzheimer's Disease and also links high levels of spherotoxin to Alzheimer's Disease. To read article click here.

AstraZeneca PLC initiates 2 Phase III clinical trials of Cerovive for stroke. To read article click here.

Proteoglycan Technologies Inc. receives US patent No. 6,563,016 B1 entitled "Perlecan Transgenic Animals and Methods of Identifying Compounds for the Treatment of Amyloidoses." To read article click here.

Eli Lilly and Company to invest $350 million in its UK business operations over the next four years. To read article click here.

Merck KGaA pays $6 million to Systems Inc. for Erbitux™ milestone. To read article click here.

-5/26/2003-

No news. Memoria Day in the US.

-5/23/2003-

Generex Biotechnology Corp. ends diabetes collaboration with Eli Lilly & Co. for Oralin insulin spray. To read article click here.

Encelle Inc.™ receives $1.7 million grant from NIH for the development of E-Matrix™ for treatment of diabetic foot wounds. To read article click here.

GeneProt Inc. licenses protein to Novartis Pharma AG. To read article click here.

GlycoDesign Inc. receives 2 U.S. for its ATH technology. To read article click here.

Antigen Express receives $357,000 SBIR grant for novel HIV DNA vaccine. To read article click here.

-5/22/2003-

Press Release: A new version of the compact Katana Lab robot from IMiX GmbH is available configured and programmed to automate the weighing process that is often used for the quality controlled filling of bottles or vials, tablets into blister packs and other similar tasks. To read press release click here.

Press Release: Frost & Sullivan's Analysis of the World Structural Proteomics Market. To read press release click here.

Roche Holding AG and Maxygen Inc. sign a $230 million deal to develop next-generation interferon alpha and beta variants targeting hepatitis. To read article click here.

Delcath Systems Inc. goes IPO. To read article click here.

Imclone Systems Inc. to remain listed on Nasdaq. To read article click here.

ThromboGenics Ltd. completes Phase I clinical trial of its drug microplasmin for the treatment of thromboembolic diseases. To read article click here.

Foot cream containing L-arginine restores feet health in diabetics suffering circulatory blood problems. To read article click here.

WuXi PharmaTech Ltd. and Merck & Co. Inc. form research collaboration where WuXi PharmaTech will provide its research chemistry facilities to accelarte Merck's drug discovery programs. To read article click here.

Infotrieve announces its "E-100" electronic document delivery initiative to deliver articles and documents directly to customers. To read article click here.

Genetic Technologies Limited licenses its non-coding patents to The University of Utah at Salt Lake City for research. To read article click here.

AstraZeneca Plc invests $145 million in a new manufacturing facility Bristol, England, for the production of its cholesterol regulating drug Crestor. To read article click here.

OctoPlus and CytImmune Sciences Inc. form anti-cancer research collaboration to develop gold nanoparticles as carriers to deliver the anticancer protein tumor necrosis factor (TNF) directly to tumors. To read article click here.

Valentis Inc. lincenses its lipid delivery technologies to Juvaris BioTherapeutics. To read article click here.

-5/21/2003-

Press Release: Guava Technologies, a biotechnology company, announces a new suite of single cell tests (assays) for biologists to easily gain a complete and highly quantitative profile of the stages of cell death or apoptosis. To read press release click here.

MDL Information Systems Inc. (MDL®) releases MDL Decision Manager system for drug discovery. To read article click here. MDL provides software and databases for combinatorial chemistry, drug discovery and HTS. For a review of MDL's software for combinatorial chemistry here at CombiChem Lab click here.

Bruker BioSpin GmbH to acquire the Superconductor Business of Vacuumschmelze GmbH & Co. KG. To read article click here. Bruker AXS Inc. offers its D8 DISCOVER System for fast X-Ray diffraction screening analysis of combinatorial libraries. For a review on Bruker AXS's D8 DISCOVER System here at CombiChem Lab click here. Bruker Daltonics Inc. provides mass spectrometer systems for drug discovery applications. To read a review of Bruker Daltonics' Mass Spec systems here at CombiChem Lab click here.

Zymark Corporation's software interface iLink™ will be included in two of Molecular Devices' new next generation microplate readers: the Analyst GT and the Gemini EM. To read article click here. Zymark Corporation provides automated systems for combinatorial chemistry and drug discovery. For a review of Zymark's systems for combinatorial chemistry here at CombiChem Lab click here.

Amgen Inc. forms cancer collaboration with Tularik Inc. commiting $125 million for research. To read article click here.

Lorus Therapeutics to move GTI-2501 to Phase II clinical trials for prostate cancer treatment. To read article click here.

CytRx Inc. licenses experimental DNA-based HIV vaccine from the University of Massachusetts Medical School in Worcester, Massachusetts. CytRx Inc. also receives a $15 million grant from NIH to take the vaccine to Phase I clinicals. To read article click here.

Schering-Plough Corp. receives European Union approval for the drug Remicade for the treatment of Crohn's disease and ankylosing spondylitis. To read article click here.

Vion Pharmaceuticals Inc. to start Phase II clinical trials of Triapine combined with gemcitabine for the treatment of metastatic or advanced non-small-cell lung cancer. To read article click here.

Oncolytics Biotech Inc. receives U.S. patent 6,565,831 entitled "Method of Preventing Reovirus Recognition for the Treatment of Cellular Proliferative Disorders." To read article click here.

Wyeth and Takeda Chemical Industries Ltd. to change the name of their venture company Wyeth Lederle Japan Ltd. to Wyeth K.K. To read article click here.

QuatRx Pharmaceuticals Company acquires exclusive worldwide rights to ILEX Oncology Inc.'s orally active compounds for the treatment of lipid disorders. To read article click here.

-5/20/2003-

Press Release: The IlluminatIR™ from SensIR Europe transforms a commercial light microscope into a versatile infrared microprobe - a spectroscopic tool for exploring the molecular structure of microsamples. To read press release click here.

Aventis Pharmaceuticals to deploy SciQuest Inc.'s LifeCycle™ Biologicals Manager sample inventory at two worldwide sites. To read article click here. SciQuest provides software applications for R&D including the Analytical Chemical Manager (ACM) for combinatorial chemistry analytical data tracking and handling. For a review on SciQuest's Analytical Chemical Manager (ACM) here at CombiChem Lab click here.

FDA approves Novartis AG's drug Gleevec (Glivec, STI571), the first tryrosine kinase inhibitor to hit the market, for the treatment of leukemia in children. To read article click here.

King Pharmaceuticals Inc. acquires Elan Corp.'s patent rights of the drugs Skelaxin and Sonata for $750 million. To read article click here.

GlaxoSmithKline and Medivir sign licensing agreement for the nucleoside analogue reverse transcriptase inhibitor MIV-210 for HIV treatment. To read article click here.

Medtronic Inc. gets European regulatory approval of its Gatekeeper™ Reflux Repair System for acid reflux treatment. To read article click here.

Viragen Inc. files patent application for natural human leukocyte-derived alpha interferon for severe acute respiratory syndrome (SARS) treatment. To read article click here.

CollaGenex Pharmaceuticals Inc. and EpiTan Ltd. form devlopment collaboration for EpiTan's melanin-promoter drug Melanotan. To read article click here.

Inspire Pharmaceuticals's nasal spray drug INS37217 for treatment of perennial allergic rhinitis (hay fever) fails clinical trials. To read article click here.

Ranbaxy Laboratories Limited and the "Medicines for Malaria Venture" form research collaboration for the development of synthetic peroxide anti-malarial drug. To read article click here.

Plexxikon Inc. and Genentech Inc. form drug discovery collaboration for novel small molecule therapeutics for cancer treatment. To read article click here.

Cumbre Inc. receives Phase I NIH/SBIR grant for grant entitled "Novel inhibitors of Mycobacterium tuberculosis RNA Polymerase." To read article click here.

Novogen Limited receives U.S. patent for its isoflavone technology to treat menopause and pre-menstrual syndrome (PMS) symptoms. To read article click here.

Virtual Arrays Inc. changes its name to Vitra Bioscience. To read article click here.

-5/19/2003-

Chiron Inc. to acquire british vaccine maker PowderJect for $881 million. To read article click here.

Eden Bioscience Corp. cut its work force by 34.5 percent. To read article click here.

Judge rules class-action suit against Martha Stewart can proceed. To read article click here.

Affymetrix Inc. to receive $1.45 million in damages from a counter lawsuit filed against Harvard Bioscience Inc. To read article click here.

Former Sepracor Inc. manager Timothy Potter pleads guilty to insider trading charges. To read article click here.

Isis Pharmaceuticals Inc. and Ercole Biotech Inc. form antisense drug discovery collaboration to regulate alternative RNA splicing. To read article click here.

-5/16/2003-

Nymox Pharmaceutical Corporation will sponsor the "Fourth Manhattan Alzheimer's Disease Conference" on May 27, 2003, in New York City, NY. To read article click here.

Curis Inc. terminates neurology joint venture with Elan Corp PLC. To read article click here.

ARIAD Pharmaceuticals Inc. discovers cause of human heart failure using its proprietary cell-signaling regulation technology. To read article click here.

ChondroGene Limited to acquire GeneNews Inc. To read article click here.

Texas Biotechnology Corporation changes its name to Encysive Pharmaceuticals. To read article click here.

Bio-Rad Laboratories' rapid test for detecting aspergillus infection is approved in the U.S. To read article click here.

Antitrust lawsuits against AstraZeneca dismissed. To read article click here.

Genaissance Pharmaceuticals Inc. and Prometheus Laboratories expand agreement for thiopurine S-methyltransferase diagnostic test. To read article click here.

Matrix Laboratories Ltd. to supply GlaxoSmithkline Plc with the anti-viral acyclovir drug. To read article click here.

Aventis will not seek regulatory approval for cardiovascular drug cariporide. To read article click here.

-5/15/2003-

Press Release: Genevac Ltd. releases new free PC utility for a wide variety of parameters coversions: The Genevac Unit Conversion Programme. To read press release click here. Genevac Ltd. provides high-throughput centrifugal evaporation systems for combinatorial chemistry, high-throughput screening (HTS) and drug discovery. To read a review of Genevac's systems here at CombiChem Lab click here.

Press Release: Genetix have successfully automated the time-consuming and laborious steps of yeast 2-hybrid (Y2H) screening, turning this into a high-throughput method to examine protein-protein interactions. To read press release click here.

LION bioscience AG launches its new ADME technology for drug discovery & lead optimization: iDEA pkEXPRESS™. To read article click here. LION offers its iDiscovery™ technologies and services for drug discovery. For a review of Lion's services here at CombiChem Lab click here.

StemCells Inc. could be deslisted from Nasdaq. To read article click here.

PHASE-1 expands tissue genomics services. To read article click here.

Federal court dismisses antitrust lawsuit regarding Barr Laboratories Inc.'s breast cancer drug Tamoxifen. To read article click here.

Paradigm Genetics Inc. receives U.S. patent 6,562,624 entitled "Methods and Materials for the Rapid and High Volume Production of a Gene Knock-Out Library in an Organism." To read article click here.

ChemGenex Therapeutics Inc. moves forward anticancer drug Quinamed™ (amonafide) to Phase I/II clinical trials. To read article click here.

Lynx Therapeutics Inc. and Millennium Pharmaceuticals Inc. form gene expression research collaboration. To read article click here.

Vicuron Pharmaceuticals Inc. and Pfizer Inc. to continue antibiotics collaboration around new oxazolidinone class. To read article click here.

-5/14/2003-

Press Release: The Tecnomouse from INTEGRA Biosciences is a hollow fibre in-vitro cell cultivation system offering optimised production of monoclonal antibodies and expression of cell products over a period of months avoiding the need for laboratory animals. To read press release click here.

The Strategic Research Institute (SRI) will host the 5th Annual "Anti-Cancer Drug Discovery & Development Summit" conference on June 30-July 2, 2003, in Philadelphia, PA. To read article click here. SRI promotes and hosts a broad range of scientific oriented conferences. For more information on SRI here at CombiChem Lab click here.

Rosetta Biosoftware and Agilent Technologies Inc. launch the Rosetta Luminator system version 2.0 for microarray applications. To read article click here. Agilent Technologies provides high-throughput HPLC analytical systems for combinatorial chemistry and drug discovery. For a review of Agilent's analytical systems here at CombiChem Lab click here.

The Center for Pharmaceutical Training will host "The Oral Drug Delivery Strategies Summit 2003" from September 29-October 1, 2003, in Philadelphia, PA. To read article click here.

Transkaryotic Therapies Inc. under investigation by the federal Securities and Exchange Commission. To read article click here.

Researchers from the National Cancer Institute (NCI) develop mouse model of the premature aging syndrome known as Hutchinson-Gilford Progeria Syndrome (HGPS). To read article click here.

Sepracor Inc. under investigation by the federal Securities and Exchange Commission. To read article click here.

A former Fox News television producer who contracted hepatitis A in Afghanistan after being inoculated sues Merck & Co. for faulty vaccine. To read article click here.

New Medicine's Oncology KnowledgeBASE (nm|OK) has been updated with 286 anticancer agents. For more information click here and here.

Evotec Technologies GmbH launches its CellProcessor instrument Elektra. To read article click here.

Isis Pharmaceuticals Inc. initiates Phase I clinical trial of ISIS 113715 for Type 2 diabetes. To read article click here.

-5/13/2003-

Press Release: For studying the expression of thousands of genes in parallel, the new QArray2 is a high-throughput, fully featured microarrayer from Genetix that is ideal for accurate, high-density arraying of cDNAs, oligos and proteins. To read press release click here.

Applied Biosystems Group launches the Mouse Assays-on-Demand™ Gene Expression Products. To read article click here. Applied Biosystems/MDS Sciex provides mass spectrometer systems for combinatorial chemistry and drug discovery. For a review of Applied Biosystems/MDS Sciex's systems here at CombiChem Lab click here.

Applied Biosystems Group makes available the Applied Biosystems 7900HT Micro Fluidic Card. To read article click here. Applied Biosystems/MDS Sciex provides mass spectrometer systems for combinatorial chemistry and drug discovery. For a review of Applied Biosystems/MDS Sciex's systems here at CombiChem Lab click here.

FDA approves Millennium Pharmaceuticals Inc.'s anticancer drug proteasome inhibitor Velcade™ (bortezomib) for blood cancer multiple myeloma treatment. To read article click here.

US panel recomends approval of Bristol-Myers Squibb's drug Reyataz™ for HIV/AIDS treatment. To read article click here.

CryoCath Technologies Inc. receives US patent 6,546,932 for angiogenesis stimulation technology. To read article click here.

The Society of Interventional Radiology reports that islet cell transplant technology corrects diabetes Type-1 in insuline-defficient patients. To read article click here.

Egea Biosciences Inc. and Centocor Inc. form protein drug pptimization collaboration. To read article click here.

Nymox Pharmaceutical Corporation 's AlzheimAlert™ test allow the monitoring of Alzheimer's disease (AD). To read article click here.

Ecopia BioSciences Inc. discovers new chemical entity with antifungal activity: ECO-14401. To read article click here.

Innaphase Corp. to acquire the U.S. assets of Beckman Coulter Inc. To read article click here.

Hemispherx Biopharma Inc. and the Genome Institute of Singapore form SARS research collaboration. To read article click here.

Lorus Therapeutics Inc. receives U.S. patent entitled "Antisense Oligonucleotide Sequences As Inhibitors of Microorganisms." To read article click here.

-5/12/2003-

Press Release: Drawing upon its experience as a leader in Electrochemical Detection for Liquid Chromatography, ESA has developed a validated HPLC method for the sample preparation and analysis of fat-soluble vitamins and related micronutrients in human serum. To read press release click here.

ImClone Systems Inc. faces deslinting from NASDAQ. To read article click here.

Arena Pharmaceuticals to adpot and deploy InnaPhase Corporation's Watson™ Laboratory Information Management System (LIMS). To read article click here.

Pharmaceuticals Ltd. moves its second generation oral LSAID™ (Leukocyte Selective Anti-Inflammatory Drug) IPL512,602 to Phase II clinical trials. To read article click here.

United States bankruptcy judge gives Genaissance Pharmaceuticals Inc. approval to aquire all the assets of DNA Sciences Inc. To read article click here.

Genentech Inc. and Xoma Ltd.'s psoriasis drug Raptiva fails trials for treatment of rheumatoid arthritis. To read article click here.

Human Genome Sciences Inc. signs exclusive worldwide license agreement with Abgenix Inc. to develop human monoclonal antibody for the human chemokine receptor CCR5 for HIV/AIDS treatment. To read article click here.

-5/09/2003-

Press Release: Porvair Sciences has announced a new high volume 24-well microplate. To read press release click here.

Press Release: Porvair Sciences, specialists in innovative microplate technology, have announced that they can offer custom-made microplates in high volumes at internationally competitive prices and on short lead times. To read press release click here.

Press Release: ESA Analytical has recently announced the development of a number of new techniques to address the need for more relevant property data earlier in the drug development process. To read press release click here.

The Institute for International Research (IIR) will host the "World Nano-Economic Congress" conference on September 8-10, 2003, in Washington, DC. For more information and early registration click here.

Indiana University, in Bloomington, IN, will host the "38th National Organic Symposium" on June 8-12, 2003. Final registration deadline: May 16, 2003. For more information and early registration click here.

The Laboratory Robotics Interest Group (LRIG) will host its "9th Annual Technology Exhibition & Presentations" Mid Atlantic conference on May 19, 2003, in East Brunswick, NJ. For more information and registration click here.

CombiMatrix Corp. and Toppan Printing Co. Ltd. form alliance to make electrochemical microarrays for drug and diagnostic tool development. To read article click here.

Bayer Corp. to pay $5.6 million to settle lawsuit from the US goverment for overcharing for its antibiotic Cipro and its high blood pressure drug Adalat. To read article click here.

Symyx Technologies Inc. to launch Symyx Therapeutics Inc. To read article click here.

ARIAD Pharmaceuticals Inc. and DiscoveRx Corporation form alliance to develope and commercialize drug-discovery assays using ARIAD's NF-(kappa)B patents. To read article click here.

Novartis AG acquires Pfizer Inc's drug Enablex for incontinence and makes major investment in Idenix Pharmaceuticals. To read article click here.

-5/08/2003-

Press Release: Tecan UK has announced the introduction of the GENios Pro detection device. To read press release click here. Tecan provides the ChemSystem workstation and the TECAN MiniPrep systems for combinatorial chemistry and drug discovery. To read a review of TECAN's systems here at CombiChem Lab click here.

Press Release: Tecan UK has announced the availability of a new global newsletter that provides researchers with a broad overview of the latest innovations in laboratory automation. To read press release click here. Tecan provides the ChemSystem workstation and the TECAN MiniPrep systems for combinatorial chemistry and drug discovery. To read a review of TECAN's systems here at CombiChem Lab click here.

The Strategic Research Institute (SRI) will host the "Metabolic Diseases Drug Discovery World Summit" conference on July 28-29, 2003, in San Diego, CA. To read article click here. SRI promotes and hosts a broad range of scientific oriented conferences. For more information on SRI here at CombiChem Lab click here.

King Pharmaceuticals Inc. firm in its decision: it will not acquire the U.S. rights to two drugs from Elan Corp. To read article click here.

Kansas State University to launch Wildcat Genetics to sell Monsanto Co.'s soybean seeds. To read article click here.

Protein Design Labs Inc.'s experimental drug for asthma targeting Interleukin-4 fails Phase II clinical trials. To read article click here.

Roche's psoriasis drug Soriatane found to cause depression. To read article click here.

ConjuChem Inc. to begin US clinical trials of its DAC(TM):GLP-1 compound for Type 2 diabetes treatment. To read article click here.

Novogen Ltd. initiates Phase II study of Glucoprime for the treatment of vascular skin ulcers. To read article click here.

Guilford Pharmaceuticals Inc. to license its NAALADase program targeting neurodegenerative diseases to Pfizer. To read article click here.

Xpogen Inc. licenses its bioinformatics software PathlinX™ 3.0 to Johns Hopkins Medical Center. To read article click here.

Accelerate Brain Cancer Cure (ABC(2)) and Genentech Inc. form brain cancer research collaboration for clinical trial studies of HER1/EGFR tyrosine kinase inhibitor Tarceva™ (erlotinib HCl) in glioblastoma multiforme (GBM). To read article click here.

Dendreon Corporation develops antigen-based alternative reading frame (ARF) technology targeting telomerase for cancer immunotherapy. To read article click here.

-5/07/2003-

Press Release: INTEGRA Biosciences, a leading international supplier of innovative lab equipment and supplies for cell cultivation, liquid handling and sterilisation applications has announced the launch of its redesigned and expanded website. To read press release click here.

The Center for Business Intelligence (CBI) announce additions to its Pharmaceutical Conference Series in 2003. To read article click here. CBI organizes and hosts a series of conferences in the pharmaceutical areas. For more information on CBI here at CombiChem Lab click here.

IBC to host the "8th Annual Drug Discovery Technology™ World Congress" conferences on August 10-15, 2003, in Boston, MA. Peer-reviewed posters to be published in Preclinica™. For more information on this conference click here. IBC promotes and hosts a broad range of scientific oriented conferences. For more information on IBC here at CombiChem Lab click here.

CombiMatrix synthesizes small interfering RNA molecules targeting specific genes of SARS virus. To read article click here.

Affymetrix Japan K.K. reach agreement with four companies to provide services for Affymetrix in Japan. To read article click here.

ChemAxon releases its Java database engine JChem 2.0 along with new tool sets for pharmacophore screening, structure standardization, RECAP fragmentation, reaction modeling and metabolite prediction. To read article click here.

Neurochem Inc. to license its proprietary diabetes technology to Innodia Inc. To read article click here.

Simulations Plus Inc. and GlaxoSmithKline expand license agreement for Simulation Plus' ADME simulation software QMPRPlus™ and GastroPlus™. To read article click here.

Panacea Pharmaceuticals Inc. and Olympus Optical Co. Ltd. form research collaboration for array assay development. To read article click here.

Argenta Discovery Ltd and Corcept Therapeutics form drug discovery and optimisation research collaboration for Corcept's psychiatric disorder programs. To read article click here.

PamGene International B.V. grantes further rights to Olympus Optical Co. Ltd. to market PamGene's flow-through microarray technology. PamGene to focus on launching its 96-array system for high throughput applications. To read article click here.

Bayer AG settles 785 lawsuits related to its cholesterol-lowering drug Baycol for $240 million. To read article click here.

Roche Holding AG will launch 6 Gene Chips tests in the next year and a half for medical diagnostics. To read article click here.

-5/06/2003-

Press Release: Autoscribe Ltd., specialists in laboratory software solutions, announces the availability of the Varian Galaxie chromatography data system. To read press release click here.

Press Release: Using state-of-the-art laboratory automation and advanced molecular techniques scientists at the BC Cancer Agency's Michael Smith Genome Sciences Centre in Canada have completed the first publicly available draft sequence for a corona virus implicated in SARS. To read press release click here.

Press Release: Científica opens new offices, expands consulting business, spins out new company. To read press release click here.

Tecan US releases Gemini 4.1 and Magellan Tracker 4.0 software. To read article click here. Tecan provides the ChemSystem workstation and the TECAN MiniPrep systems for combinatorial chemistry and drug discovery. To read a review of TECAN's systems here at CombiChem Lab click here.

Bio-Tech Israel 2003 will be held from May 13 - 15, 2003, in Tel Aviv, Israel. To read article click here.

AstraZeneca files patent lawsuite against KV Pharmaceuticals to block generic form of AstraZeneca's heart drug Toprol. To read article click here.

Schering AG and Astex Technology Ltd. sign multi-target drug discovery alliance focusing on cancer drugs. To read article click here.

Johnson & Johnson Co. to buy the medical products company Link Spine Group Inc. for $325 million. To read article click here.

Immunomedics Inc. receives U.S. patent 6,558,669 for antibody labeling methodology with Iodine-131 (I¹³¹). To read article click here.

AVANIR Pharmaceuticals receives $100,000 SBIR grant from NIH to develop human monoclonal antibodies for the treatment of human cytomegalovirus. To read article click here.

Neurogenetics Inc. to license AMPA/Kainate receptor antagonist compound from Eli Lilly and Company for pain treatment. To read article click here.

Nexia Biotechnologies Inc. to cut a third of its staff. To read article click here.

Affymetrix arrays SARS genome map sequence on gene chip. To read article click here.

MWG Biotech AG and Hitachi Software Engineering form microarray collaboration. To read article click here.

Micronics Inc. and the Hybrid Systems Laboratory of the Department of Bioengineering at Clemson University form research collaboration to explore materials & surface chemistries on miniaturized fluid processes. To read article click here.

-5/05/2003-

Pfizer Inc. to expand its New York City operations investing $1 billion and adding 1,000 positions over the next 15 years. To read article click here.

FDA approves AstraZeneca's anticancer kinase inhibitor drug IRESSA® (gefitinib, ZD1839) for the treatment of advanced non-small cell lung cancer (NSCLC). To read article click here.

La Jolla Pharmaceutical Corp. will try to get FDA's approval for its lupus drug Riquent™. To read article click here.

Serenex Inc. and GlaxoSmithKline form alliance to incorporate Serenex's novel chemoproteomics technologies into selected GSK drug discovery programs. To read article click here.

Hemispherx Biopharma Inc. and the Center for Cell and Gene Therapy at the Baylor College of Medicine in Houston, Texas, form research collaboration for the Ampligen for immune clinical trails. To read article click here.

-5/02/2003-

Pfizer announces changes at the Pharmacia's New Jersey facilities including $400 million investment to expand NJ operations over the next five years. No comment on any potential layoffs. To read article click here.

Two of GlaxoSmithKline's patents for the antibiotic Ceftin to expire in July of 2003. To read article click here.

FDA approves Aldurazyme, developed by Genzyme General Corp. and BioMarin Pharmaceutical Inc., for treating of the rare genetic disease called MPS 1 that causes progressively damages organs and often kills patients before they reach adulthood. To read article click here.

Génome Québec and CGI Group Inc. from partnership to create an integrated and comprehensive bioinformatics platform. To read article click here.

The Public Citizen urges FDA not to approve AstraZeneca's anticancer drug IRESSA (gefitinib, ZD1839) based on 173 deaths in Japan's clinical trials. To read article click here.

Essential Therapeutics Inc. files for Chapter 11 bankruptcy protection. To read article click here.

-5/01/2003-

IBC Life Sciences opens its Training Academy offering over 120 professional development courses throughout the 2003 calendar year. To read article click here. IBC promotes and hosts a broad range of scientific oriented conferences. For more information on IBC here at CombiChem Lab click here.

IBC to host the "Model Organisms in Drug Discovery" conferences on August 12-13, 2003, in Boston, MA. For more information on this conference click here. IBC promotes and hosts a broad range of scientific oriented conferences. For more information on IBC here at CombiChem Lab click here.

Introgen Therapeutics Inc. in-licenses the anticancer gene fus1 from the University of Texas to develop lung cancer drugs. To read article click here.

AstraZeneca gets australian approval of IRESSA (gefitinib, ZD1839) for the treatment of non-small cell lung cancer (NSCLC). To read article click here.

Schering-Plough Corp.not interested in merging with Merck & Co. To read article click here.

Syrrx Inc. and RTS Life Science International form partnership to develop and market the HTSB Factory™ for high throughput structural biology. To read article click here.

ARIUS Research Inc. and the Ottawa Regional Cancer Centre form ovarian cancer research. To read article click here.

Diversa Corporation and DuPont enter 6-year collaboration for biocatalysts discoveyr and development. To read article click here.