FOR IMMEDIATE RELEASE

December 9, 2003.

ESA Analytical have announced a series of new applications briefs demonstrating the utility of its ChromaChem Evaporative Light Scattering Detector for the analysis of a range of natural products.

Analysis of complex natural products ..

ESA Analytical have announced a series of new applications briefs demonstrating the utility of its ChromaChem Evaporative Light Scattering Detector for the analysis of a range of natural products.

The Chromachem® Evaporative Light Scattering Detector is a mass sensitive device, which produces a response directly proportional to an analyte's mass in the sample. Unlike HPLC UV or fluorescence detectors the Chromachem does not require the presence or absence of chromophores, fluorophores or electroactive groups for detection.

Incorporating a unique nebulisation system, state-of-the-art electronics, high intensity polychromatic light source and low noise photomultiplier the Chromachem offers sensitivity better than RI or low wavelength UV HPLC detectors enabling detection of even minor natural product components.

Insensitive to temperature variation the highly stable system also provides leading-edge consistency in measurement of relative response factors. As a consequence direct assessment of relative mass is possible, without standards, saving time and making HPLC-ELSD the most versatile of techniques. For a copy of the new application briefs and further information on the Chromachem Evaporative Light Scattering Detector please contact ESA Analytical Ltd.

European HQ ESA Analytical Ltd. Brook Farm Dorton, Aylesbury Bucks. HP18 9BH UK tel. +44-1844-239381 email: egoodall@esainc.com www.esainc.com