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FOR IMMEDIATE RELEASE

January 30, 2003

MDL® and SciTegic® form strategic alliance.

-MDL will market SciTegic's data analysis and mining tool, Pipeline PilotTM; Companies to explore product integration-

SAN LEANDRO, CA and SAN DIEGO, CA-January 30, 2003-MDL Information Systems, Inc. (MDL®) and SciTegic, Inc., the leader in discovery data pipelining software, have announced a collaboration focused on SciTegic's innovative data analysis and mining tool, Pipeline PilotTM. Under the agreement, MDL will co-market Pipeline Pilot in the life science informatics field, offer consulting services related to the product, and license Pipeline Pilot for internal use. The companies are exploring areas of integration between their respective products.

"SciTegic Pipeline Pilot is an innovative and invaluable tool for pharmaceutical and biotechnology researchers in today's data-rich environment," said MDL President and CEO Pat Rougeau. "When used together, MDL Discovery Framework and data pipelining offer powerful management and analysis capabilities that can help our customers master the unprecedented volumes of data created in discovery research."

"MDL's unparalleled experience and leadership in discovery informatics makes it the perfect partner to deliver SciTegic's data pipeline technology to researchers," said Mathew Hahn, Ph.D., President and CEO of SciTegic. "Pipeline Pilot complements the informatics infrastructures that MDL customers have in place and provides for tremendous flexibility in analysis of diverse collections of data."

Pipeline Pilot is a new high-throughput data analysis and mining tool for drug discovery informatics that can be used to define and automate complex operations on extremely large data sets. The technology complements general informatics and database systems including MDL's Discovery Framework for managing chemical and biological information.

By marketing Pipeline Pilot, MDL will offer a highly customizable means to process and analyze the growing volume of data generated in modern automated laboratories. MDL currently provides a comprehensive suite of industry-standard technology, applications, and content databases that allow life scientists to capture, manage, integrate, interpret, and share discovery data. The addition of Pipeline Pilot will further strengthen that portfolio and provide customers with an even greater range of information management options.

Pipeline Pilot solves common interdisciplinary and inter-organizational research problems by collectively processing whole data sets of disparate types. For example, Pipeline Pilot can be used to evaluate a vendor's compound library against a company's internal collection, or mine different chemical databases for candidate leads, while simultaneously applying outside criteria from text collections and other scientific domains. The system can also prioritize compounds for screening using both stored properties and derived properties calculated in real time.

Under the agreement, MDL becomes a worldwide co-exclusive marketer of the Pipeline Pilot products within the cheminformatics, screening, and ADME/Tox market segments, and acquires worldwide non-exclusive rights to perform consulting services related to Pipeline Pilot. SciTegic will continue to develop, support, and market the Pipeline Pilot product in all areas of life science research.

About SciTegic
SciTegic, Inc. is a privately held San Diego company which develops and markets informatics software to the pharmaceutical and biotechnology markets. The company is pioneering a new technology approach called "data pipelining" to process drug discovery data with unprecedented flexibility. This new methodology is fast establishing its utility by accelerating informatics research for hundreds of users at dozens of customer sites
worldwide. Further information about SciTegic is available at www.scitegic.com

About MDL

Over 1,000 life science companies supercharge their discovery engines with MDL software solutions to generate fresh ideas and make breakthrough discoveries. By synchronizing and streamlining the sharing and management of vital information and knowledge, we enable scientists to work more efficiently and invent drugs faster. This saves time, money, and lives. In support of our customers and the momentous challenges they face, everything
we do must be reliable, resourceful, innovative, and insightful. We are an international business headquartered in San Leandro, CA with offices worldwide. MDL is a wholly owned subsidiary of Elsevier, Inc., which is part of the Reed Elsevier Group plc, owned by Reed Elsevier PLC (NYSE: RUK) and Reed Elsevier NV (NYSE: ENL). For more information, visit www.mdl.com


CONTACTS:

MDL Information Systems, Inc.
Dr. Phil McHale, Vice President
Corporate Communications & Scientific Affairs.
tel. (510) 895-1313 ext. 3541
email: p.mchale@mdl.com



SciTegic™, Inc.
Marty Kleine, Director
Marketing Communications
tel. (858) 279-8800 ext. 14
email: mkleine@scitegic.com

 MDL is a registered trademark in the United States of MDL Information Systems, Inc. SciTegic is a registered trademark and Pipeline Pilot is a trademark in the United States of SciTegic, Inc. All other company and/or product names may be trademarks or registered trademarks of their respective owners in the United States and other countries. All rights reserved.