FOR IMMEDIATE RELEASE

February 12, 2004.

INTEGRA Biosciences, a specialist supplier of innovative products for microbiology and cell culture laboratories, has announced strong end of year sales of over Euro 5 million.

INTEGRA Biosciences .. well positioned for growth in 2004

INTEGRA Biosciences (Chur, Switzerland), a specialist supplier of innovative products for microbiology and cell culture laboratories, has announced strong end of year sales of over Euro 5 million.

Have achieved a series of notable changes enabling the business to move strongly forward in 2003, INTEGRA Biosciences has announced a range of investments that will position the company for growth again in 2004. Notable amongst the investments are increased spending on new product development (> 12%), further development of worldwide sales channels and expanded facilities for R&D and Sales & Marketing at the Swiss headquarters.

Reflecting upon the past year, Elmar Morscher (Managing Director) commented 'completing our reorganisation has enabled us to focus resources to better serve our customers worldwide - almost all major territories have shown positive development of business levels'. He added 'listening to the needs of our customers we introduced the PIPETBOY Comfort, VACUSAFE Comfort and CELLine adhere in 2003 - these high quality products already account for 18% of our turnover'.

Further information on the PIPETBOY Comfort, a lightweight pipetter, the VACUSAFE Comfort - an aspiration system for the safe and comfortable removal of biological fluids and the CELLine adhere, a novel disposable flask-bioreactor for protein expression from adherent cells is available at www.integra-biosciences.com

CONTACTS:

Worldwide HQ INTEGRA Biosciences CHUR, Switzerland Tel: + 41 81 286 9530 Email: info@integra-biosciences.com www.integra-biosciences.com