FOR IMMEDIATE RELEASE

October 15, 2004.

The Metz Syn10 from Radleys Discovery Technologies (www.radleys.com) offers truly versatile parallel synthesis with variable heating, cooling, refluxing and stirring. The Metz Syn10 will simultaneously carry out 10 reactions, each with a different temperature, from -30°C to +150°C.

Versatile tool for optimising chemical reactions ..

The Metz Syn10 from Radleys Discovery Technologies (www.radleys.com) offers truly versatile parallel synthesis with variable heating, cooling, refluxing and stirring. The Metz Syn10 will simultaneously carry out 10 reactions, each with a different temperature, from
-30°C to +150°C.

Compact, simple to operate and easily integrated into robotic systems the Metz Syn10 is the perfect parallel synthesis system for both medicinal and process chemists looking for faster process development and reaction optimisation.

Designed for use in all types of process optimisation, parallel synthesis, chemical and catalyst development the Metz Syn10 can be used to optimise the best combination of catalyst, reagent and solvents for synthesis and evaluate the effects of changing temperature and reagent concentrations on yield and purity. The versatile system can also be used to optimise reaction times in an automated fashion as well as defining alternative synthetic routes for compound development.

The Metz Syn10 offers stirring control from 250rpm to 1200rpm, with a maximum temperature difference between any two adjacent wells of 180°C. Superior chemical resistance, gas tight sealing and easy operation are provided through proprietary PTFE capped tubes, which feature an all PTFE valve. A central inlet/outlet manifold, combined with the gas tight PTFE caps allows the introduction of inert gas for air or moisture sensitive reactions. An optional removable water-cooled Reflux unit may be used to provide even and efficient refluxing within the glass reaction tubes, minimising solvent evaporation during synthesis for even highly volatile solvents.

Complementing the versatile hardware the intuitive Metz Syn10 PC software provides a comprehensive suite of control options including individual well programming and profiling, controlled heating/cooling ramps, crash cooling function for rapid temperature changes, plus an 'on-the-fly' function for modifying profiles in progress, multi-user feature, data collection and control by solution temperature.

For further information on the Metz Syn10 please contact Radleys Discovery Technologies on telephone +44-1799-513320 or visit www.radleys.com to download a pdf brochure.

CONTACTS:

Worldwide HQ Radleys Discovery Technologies Shire Hill Saffron Walden Essex CB11 3AZ UK tel. +44-1799-513320 email: sales@radleys.co.uk