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FOR
IMMEDIATE RELEASE
June
6, 2005.
Guava
Technologies Inc. has introduced a new simple non-radioactive assay
designed to improve the performance and sensitivity of cell proliferation
assays compared to traditional population-based methods.
Easy
and sensitive cell proliferation analysis ..
Guava
Technologies Inc. has introduced a new simple non-radioactive
assay designed to improve the performance and sensitivity of cell
proliferation assays compared to traditional population-based methods
such as 3-Thymidine and MTT (or XTT).

The
Guava CellGrowth assay, when used in conjunction with the Guava
EasyCyte System, provides cell proliferation analysis at the single-cell
level, offering cell proliferation assessments without the use of
more complex fluorescence methods out to 5 generations. In addition,
the assay offers a broader linear range and is more quantitative
when compared to colorimetric methods.
The
Guava CellGrowth Assay uses a well-characterised cell tracking dye
that diffuses freely into cells and is retained within the cell
without affecting cellular function. The dye is not transferred
to adjacent cells. The Guava CellGrowth assay uses two dyes, a cell
permanent painting dye and a cell impermanent DNA binding dye, to
distinguish live or dead proliferated cells from live or dead resting
cells. For each round of cell division, the relative fluorescence
intensity of the dye is decreased by half. The assay is ideal for
monitoring the growth of primary cultures, such as peripheral blood
mononuclear cells, activated T or B cells, peripheral blood lymphocytes,
thymocytes, hematopoietic cells, splenocytes and fibroblasts.
Used
in conjunction with the Guava EasyCyte the Guava CellGrowth Assay
provides researchers with a convenient 96-well format for multiple
sample analyses increasing productivity and reducing intensive labour
costs. The assay also eliminates the costs and safety issues around
the use and disposal of toxic and radioactive chemicals.
Based
in Hayward, California, Guava Technologies is a biotechnology company
that develops, manufactures and markets unique integrated cellular
analysis systems for the life science researcher's benchtop. More
information about the company and its products is available at www.guavatechnologies.com
CONTACTS:
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